摘要
本文以Ｄ－二聚体水平及纤溶酶原活性为指标观察了４０例脑血栓及２３例脑出血病人的血浆纤溶状态。脑血栓组Ｄ－二聚体水平呈规律性变化，自病后４８ｈ内始显著上升，３～４ｄ达高峰，以后渐下降，至１月时仍高于正常对照组；纤溶酶原活性于急性期（＜１周）明显下降，病后３～４ｄ降至最低值。Ｄ－二聚体水平达高峰时与纤溶酶原活性下降呈负直线相关。脑出血后Ｄ－二聚体水平于１月内亦显著增加。
To assess the time course of fibrinolysis after acute stroke,we measured plasma concentrations of D dimer and activities of plasminogen in 40 patients with cerebral thrombosis and 23 patients with cerebral hemorrhage at various times.D dimer levels were markedly elevated in both ischemic and hemorrhagic stroke within 48 hours of onsets(P<0.001 and P<0.01,respectively).In cerebral thrombosis,D dimer concentrations continuously increased to the peak values within the first week (P<0.001),whereas in cerebral hemorrhage the peak appeared at the end of the secone week.D dimer were still maintained significantly highy levels in both kinds of stroke patients until one month after stroke (P<0.02).Plasminogen activities decreased significantly only within the first week after ischemic stroke.
出处
《中风与神经疾病杂志》
CAS
CSCD
北大核心
1997年第1期16-17,共2页
Journal of Apoplexy and Nervous Diseases
关键词
中风
脑血栓
血浆
纤溶
D-二聚体
纤溶酶原
Cerebral thrombosis Cerebral hemorrhage D dimer Fibrinolysis plasminogen
