摘要
为探讨正常孕妇和妊高征患者的血液动力学参数，采用无创妊高征血液动力学监测系统（ＭＰ－ＰＩＨ），序贯监测孕早、中、晚期正常孕妇３０例，非孕妇６０例，妊高征（轻、中、重度）患者４６例。非孕妇和正常孕妇属正常排，微循环、流量、流速、流态正常，两者无明显差异。妊高征正常排：ＣＩ（２．８５±０．３９）Ｌ．ｍｉｎ－１／ｍ２，ＡＬＫ（０．０４±０．０１）１／ｓ，ＡＬＴ（１９．５６±２．４６）ｓ，ＴＭ（２８．２３±３．５５）ｓ，与正常孕妇无显著差异。高排低阻：ＣＩ（４．８４±０．４１）Ｌ·ｍｉｎ－１／ｍ２，ＡＬＫ（０．０６±０．０１）１／ｓ，ＡＬＴ（１１．４２±０．９５）ｓ、ＴＭ（１６．４８±１．３５）ｓ。心排量＞４Ｌ·ｍｉｎ－１／ｍ２，表明心肌代偿性加强收缩，血流速加快经微循环直捷通路，缺乏与组织细胞间的营养、代谢交换。低排高阻：ＣＩ（２．０９±０．２８）Ｌ·ｍｉｎ－１／ｍ２，ＡＬＫ（０．０３±０）１／ｓ，ＡＬＴ（２６．７８±４．０２）ｓ，ＴＭ（３８．６５±５．７６）ｓ。心排量＜２．５Ｌ·ｍｉｎ－１／ｍ２，血流量少，流速慢，微循环淤血，组织细胞缺血、缺氧。
Objective:To investigate the hemodynamic parameters in normal pregnant women and the women with PIH.Design:Hemodynamic parameters including cardiac function and microcirculation were prospectively studied in 30 normal pregnancies and 46 cases of PIH.Results:Parameters of normal pregnancies:CI(3 00±0.74)L.min -1 /m 2,microcirculation ALK(0 04±0.01)1/s,ALT(19.51±4.81)s,TM(27 92±7 16)s.They were in normal range.Women with PIH:①In patients with normal cardiac output,CI(2 85±0.39)L.min -1 /m 2,ALK(0.04±0.01)1/s,ALT(19.36±2.46)s,TM(28.23±3.55)s.There was no significant difference when comparing with normal pregnancy group.②In patients with high output,CI (4.84±0.41)L.min - 1/m 2,ALK(0.06±0.01)1/s,ALT(11.42±0.9)s,TM(16.48±1.35)s.It meant that high output was the cause of compensatory myocardiac hypercontractility pushing the blood into the direct pathway with insufficient nutrition and oxygen providing tissues and cells.In patients with low output:CI(2.09±0.68)L.min - 1/m 2,ALK(0.03±0)1/s,ALT(26.78±4.02)s,TM(38.65±5.76)s.It meant that the low blood flow into microcirculation and blood stasis causes hypoxemia and ischemia of tissues and cells.Conclusion:An understanding of hemodynamic parameters,especially,the changes of microcirculatory blood flow would be helpful in deciding fluid therapy,as well as potentially useful in prevention of cardiodysfunction and pulmonary edema. \ \
出处
《中国实用妇科与产科杂志》
CAS
CSCD
北大核心
1997年第1期29-30,共2页
Chinese Journal of Practical Gynecology and Obstetrics
关键词
妊娠高血压
综合征
血液动力学
微循环
Pregnancy induced hypertension\ \ Hemodynamic\ \ Microcirculation
