摘要
神经递质对神经细胞电压依赖性离子通道具有调制作用。近年来观察到，神经递质可通过Ｇ蛋白介导对神经细胞电压依赖性离子通道直接发挥调制作用，而不经过目前已知的多种第二信使的介导，使人们对递质、Ｇ蛋白与电压依赖性离子通道间的相互关系有了新的认识。本文归纳了神经递质通过Ｇ蛋白对电压依赖性通道的直接调制的表现。
Neurotransmitters have regulative effects on voltage dependent ion channels of nerve cells. Recent studies have shown that voltage dependent channels were modulated by transmitters through direct interactions between G proteins and channels without any known second messengers being involved.This gave us a novel understanding of the relations between G proteins and voltage dependent ion channels.This article reviews the phenomena, characteristics, and mechanisms about voltage dependent channels modulated by transmitters through direct effects of G proteins.
出处
《生理科学进展》
CAS
CSCD
北大核心
1997年第1期14-18,共5页
Progress in Physiological Sciences
