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绞股蓝对脑梗塞后病人脑功能障碍的改善作用 被引量:15

Effects of Gynostemma Pentaphyllum on Cognitive Functions of Cerebral Infarct Patients
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摘要 目的:探讨绞股蓝对脑梗塞病人脑功能的改善作用。方法:在76例被试中,随机以32例脑梗塞患者服用绞股蓝(a组),21例脑梗塞患者服用脑复康(b组),23例匹配的正常老年人服用绞服蓝(c组),三组均服药12周;用CMS、WMS、HRB-RC作为观察疗效的指标。结果:(1)a组及c组在服用绞股蓝12周后,其记忆各分测验成绩及记忆商均升高,并优于b组。a组经服绞股蓝后,记忆力改善并接近正常老年人。(2)a组服用绞股蓝后神经心理测验成绩优于b组,尤其是范畴测验成绩更好,并且a组神经心理功能接近于正常老年人的水平。结论:绞股蓝能较好地改善脑梗塞患者的脑功能。这对于脑梗塞后认知功能的恢复、痴呆的预防和治疗都有价值。 Objective: To investigate the effects of Gynostemma Pentaphyllum(GP) on cognitivefunctions of cerebral infarct (CI) patients. Method:A total of 76 cases were studied, including 32 randomly selected CI patients on GP (Group A), 21 CI patients on Piracetam (Group B), and 23 matched normal elderly controls on GP (Group C). All subjects received drugs for a period of 12 weeks, and they were assessed before and after drug administration on several cognitive scales, including the Clinical Memory Scale (CMS), the Wechsler Memory Scale (WMS), and the HRB-RC. Results:(1) After the 12-week drug period, Group A obtained compatible MQ scores to Group C, while both groups showing better improvement than Group B. (2) After taking GP, Group A showed better improvement in cognitive functions than Group C, especially on the Category Test. The administration of GP improved cognitive functions of CI patients to a level close to that of normal elderly subjects.Conclusions:The present results provide support for the favourable effects of GP on improving cognitive functions of CI patients, which have significant clinical implications for the treatment and prevention of cerebral infarct conditions.
出处 《中国临床心理学杂志》 CSCD 1997年第2期65-68,共4页 Chinese Journal of Clinical Psychology
关键词 绞股蓝 脑功能 脑梗塞 中医药疗法 Gynostemma pentaphyllum, Cerebral infarcts, Cognitive functions
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