期刊文献+

原发性脾脏肿瘤的临床病理特点及外科治疗 被引量:5

Clinicopathologic features and treatment of primary splenic tumors
原文传递
导出
摘要 目的探讨原发性脾脏肿瘤的临床病理特点及外科治疗效果。方法回顾性分析1972年2月至2006年3月间中国医学科学院肿瘤医院收治的43例原发性脾脏肿瘤,按照其临床病理特点进行分类,并就治疗经过及生存率进行统计分析。结果 43例患者中经查体发现者48.8%(21例)。42例行手术切除肿瘤,1例行肿瘤活检。良性16例,其中脾血管瘤15例,脾淋巴管瘤1例;恶性肿瘤24例,其中脾淋巴瘤16例,脾血管肉瘤8例,多数淋巴瘤患者长期生存,3年生存率为88.7%,脾血管肉瘤平均生存时间为10.4个月。结论原发性脾脏肿瘤缺乏特异性症状,B 超和 CT为首选检查方法,手术切除为治疗的主要手段。 Objective To investigate the clinical pathological characteristics and treatment of primary splenic tumor. Methods The clinical data of 43 patients with primary splenic rumors, 23 males and 20 females, aged 44.7 (19-66) , treated in the Cancer Hospital, Chinese Academy of Medical Science from Feb 1972 through Mar 2006 were analyzed. Results Of the 43 cases, 21 cases (48.8%) were found in physical examination. 42 cases underwent splenectomy and 1 case underwent rumor biopsy. Sixteen cases were with benign splenic tumors, including 15 cases of hemagioma and 1 case of lymphangioma. Of the 24 malignant cases, 16 suffered from splenic lymphoma and 8 from angiosarcoma. Most lymphoma cases survived and the mean three year surviving rate was 88.7%. The mean surviving time of angiosarcoma was only 10.4 months, Conclusion Primary splenic tumors lack specificity; B-ultrasonography and CT are primary examination methods. Surgery is an effective method in treatment of primary splenic tumors.
出处 《中华医学杂志》 CAS CSCD 北大核心 2007年第24期1673-1675,共3页 National Medical Journal of China
关键词 脾肿瘤 诊断 治疗 Splenic neoplasms Diagnosis Treatment
  • 相关文献

参考文献11

  • 1Iozzo RV, Hbass JE, Chard RL. Symptomatic splenic hamartoma. Pediatrics, 1980,66:261-265.
  • 2Brostick WC. Primary splenic neoplasma. Am J Pathol, 1945,21 : 1143.
  • 3孙重波,张高嘉,王殿昌.脾脏肿瘤的诊断与治疗(附24例报告)[J].中国肿瘤临床,1993,20(8):600-602. 被引量:51
  • 4Gupta TD, Coombes B, Brasfield RD. Primary malignant neoplasms of the spleen. Surg Gynecol Obstet, 1965, 120: 947-950.
  • 5杨连粤,吕新生,黄耿文.原发性脾脏肿瘤的诊断与治疗[J].中华肝胆外科杂志,2001,7(6):331-333. 被引量:41
  • 6Vranchliotis TG, Bennett WF, Vaswani KK, et al. Primary angiosarcoma of the spleen--CT, MR and sonographic characteristics: report of two cases. Abdom Imaging, 2000, 25:283-285.
  • 7Fritscher-Ravens A, Mylonaki M, Pantes A, et al. Endoscopic ultrasound-guided biopsy for the diagnosis of focal lesions of the spleen. Am J Gastroenterol, 2003, 98: 1022-1027.
  • 8Coon WW. Surgical aspects of splenic diseas and lymphoma: benign and malignant tumors. Curt Probl Surg, 1998, 35: 600-608.
  • 9Giagroundis AAN, Burk M, Meckenstock G, et al. Pathlogic rupture of the spleen in haematologic malignancies: two additional cases. Ann Hematol, 1996,73:297-302.
  • 10Willcox TM, Speer RW, Schlinkert RT. Hemangioma of the spleen : presentation, diagnosis, and management. J Gastrointest Surg,2000 ,4 :611-613.

二级参考文献3

  • 1Andrew Mitchell M.D.,Professor Peter J. Morris Ph.D., F.R.C.S.. Splenectomy for malignant lymphomas[J] 1985,World Journal of Surgery(3):444~448
  • 2Leon Morgenstern M.D., F.A.C.S.,James Rosenberg B.A.,Stephen A. Geller M.D.. Tumors of the spleen[J] 1985,World Journal of Surgery(3):468~476
  • 3Leon Morgenstern M.D., F.A.C.S.,James Rosenberg B.A.,Stephen A. Geller M.D.. Tumors of the spleen[J] 1985,World Journal of Surgery(3):468~476

共引文献85

同被引文献34

  • 1邓侠兴,杨卫平,陈皓,尹路,彭承宏,蔡伟耀,李宏为.原发性脾脏良性肿瘤的诊断与治疗[J].临床外科杂志,2004,12(3):158-159. 被引量:7
  • 2黄跃南,郭欣,王夫景,于洪亮,杨茂鹏,王启余,杨维良.脾肿瘤的诊治进展[J].世界华人消化杂志,2006,14(4):429-433. 被引量:12
  • 3魏云海,顾凤元.脾脏肿瘤53例临床诊治分析[J].中华普通外科杂志,2007,22(3):232-233. 被引量:9
  • 4Ahmann DL,Kiely JM,Harrison EG Jr,et al.Malignant lymphoma of the spleen:a review of 49 cases in which the diagnosis was made at splenectomy.Cancer,1966,19:461-469.
  • 5Kehoe J,Straus DJ.Primary lymphoma of the spleen:clinical features and outcome after spleneetomy.Cancer,1988,62:1433-1438.
  • 6Gobbi PG,Grignani GE,pozzetti U,et al.Primary splenic lymphoma:does it exist? Haematologica,1994,79:286-293.
  • 7Hahn JS,Lee S,Chong SY,et al.Eight-year experience of malignant lymphoma-survival and prognostic factors.Yonsei Med J,1997,38:270-284.
  • 8Lichtman MA.Battling the Hematological Malignancies:The 200 Years' War.The Oncologist,2008,13:126-138.
  • 9武忠弼 杨光华主编.中华外科病理学[M].北京:人民卫生出版社,2002.646.
  • 10苏丽丽.原发性脾脏血管肉瘤的免疫组化研究[J].实用肿瘤学杂志,2007,21(5):441-442. 被引量:17

引证文献5

二级引证文献21

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部