摘要
目的 评价瑞芬太尼复合麻醉用于婴幼儿心脏手术安全性和有效性。方法 选择30例患儿,ASAⅠ～Ⅱ级,择期行房间隔缺损（ASD）或单纯室间隔缺损（VSD）修补术。随机分为2组,Ⅰ组芬太尼0.05～1μg/（kg·min）持续泵入,Ⅱ组瑞芬太尼0.05～1.00μg/（kg·min）持续泵入。分别于不同时间记录血流动力学参数,并采集动脉血标本测量应激激素浓度,观察术后机械通气时间和拔管时间。结果 与Ⅰ组比较,Ⅱ组在术中各时点血流动力学参数和应激激素浓度差异均无统计学意义,但术后通气时间和拔管时间均显著缩短（P〈0.01）。结论 瑞芬太尼复合麻醉维持术中血流动力学稳定,有效抑制应激激素释放,术后能早期拔管,适用于婴幼儿心脏手术快通道麻醉。
Objective To evaluate the efficiency and safety of remifentanil combined anesthesia in infants and children undergoing ventricular septal defect repair. Methods Thirty infants and children with atrial septal defect or simple ventricular septal defect who were deemed suitable for fast track anesthetic management were included in this study. They were randomized into two groups. Group I with continuously infusion of fentanyl at 0. 05-1.00ug/kg＊min, group II with continuously infusion of remifentanil at 0. 05-1.00ug/kg＊min. The hemodynamics parameters and blood level of stress homone at different time points during the operation were monitored. The duration of mechanical ventilation and extubation time were also recorded. Results There was no significant difference between the two groups on hemodynamics parameters and blood level of stress homone. The duration of mechanical ventilation and extubation time in group II were notably shorter than those of group I.Conclusion The results of this study success- fully used for fast track anesthesia in elected infants and children with atrial and simple ventricular seDtal defects.
出处
《国际医药卫生导报》
2007年第12期80-83,共4页
International Medicine and Health Guidance News
关键词
瑞芬太尼
婴幼儿
心脏快通道麻醉
应激激素
remifentanil Infants Fast track cardiac anesthesia Stress homone
