摘要
目的:探讨瑞芬太尼联合曲马多用于儿童扁桃体腺样体手术麻醉的可行性和临床效果。方法:扁桃体腺样体手术患儿40例,随机分为芬太尼组(A组)和瑞芬太尼组(B组)各20例,分别以瑞芬太尼泵注及芬太尼静脉注射诱导及麻醉维持,B组在手术结束前静脉注射曲马多,观测两组患儿血流动力学变化及术后恢复情况。结果:B组在插管后即刻、腺样体切出时HR、MAP低于A组(P<0.05);A组MAP、HR在插管后即刻、腺样体切出时均高于麻醉诱导前(P<0.05),B组各时点变化差异无统计学意义(P>0.05),B组拔管时间比A组短(P<0.05),且苏醒更平稳。结论:瑞芬太尼联合曲马多用于儿童扁桃体腺样体手术可行且临床效果满意。
Objective： To investigate the feasibility and clinic effect of anesthesia with remifentanil/tramadol in tonsillectomy and adenoidectomy. Methods： Forty patients undergoing elective tonsillectomy and adenoidectomy were randomly divided into two groups： fentanil group （A） and remifentanil group （B） （ n = 20）. Group A received induction and intravenous injection with fentanil, and group B received induction and continuous infusion with remifentaniland and tramadol was given intravenously before the operation termination. The following parameters were monitored： MAP and HR and postoperation recovery was observed. Results： MAP and HR were lower in group B than in group A when endotracheal catheter was put in and adenoidectomy done （ P 〈 0.05）. MAP and HR were higher in group A at the time when endotracheal catheter was put in and adenoidectomy done than before induction of anesthesia （P 〈 0.05）. But MAP and HR showed no significant changes statistically in group B （P 〉 0.05 ）. Conclusions： Remifentanil/tramadol can be applied safely in pediatric tonsillectomy and adenoidectomy.
出处
《儿科药学杂志》
CAS
2007年第3期39-41,共3页
Journal of Pediatric Pharmacy
