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复方丹参对小鼠急性重度肝损伤的保护作用 被引量:2

Effect of miltiorrhizae Co on prevention and treatment of serious acute liver injury in mouse
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摘要 用25%CCl_4复制小鼠急性重度肝损伤,以复方丹参(A组,N=10)和生理盐水(B组,N=9)预处理三天。两组结果比较表明,A组的肝受损程度较轻(P<0.05),肝坏死灶的平均直径较小(P<0.01)。结果提示,复方丹参对急性重度肝损伤具有防治作用。 The serious acute liver injury in 19 mice was caused by means of 25%CC14. These mice had been divided into two groups and pretreated for three days with Inj. Salviae Miltiorrhizae Co. in Group A (n = 10) and with salin in Group B (n = 9). The results showed that the degree of liver injury was minor ( P<0.05)and the relative value of necrotic area of liver tissues was smaller ( P<0.01 ) in Group A. It suggested that Inj. Salviae Miltiorrhizae Co. could prevent and treat serious acute liver injury.
出处 《赣南医学院学报》 1990年第4期215-217,共3页 JOURNAL OF GANNAN MEDICAL UNIVERSITY
关键词 病毒性肝炎 丹参 药效 小鼠 Hepatitis, toxic/drug therapy Radix salviae miltiorrhizae /pharmacodynamics Liver/pathology
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  • 1马丽英,王孝铭,张国义,梁殿权,李晖.丹参制剂对家兔缺血心肌腺苷酸类代谢的影响[J]中国病理生理杂志,1988(02).
  • 2姚睦,荣烨之,温文虎.再灌注与自由基:再灌注损伤机制的探讨[J]国外医学心血管疾病分册,1987(02).

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