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冠状动脉病变与血尿酸水平的关系探讨 被引量:3

The relationship between coronary artery lesions and the levels of serum uric acid
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摘要 目的了解不同程度冠状动脉病变患者血尿酸水平的变化。方法64例患者行冠状动脉造影,以冠脉病变程度分组,同时检测空腹血尿酸水平。结果血尿酸水平:冠状动脉正常组(0支组)为(0.30±0.06)mmol/L,冠状动脉1支病变组(1支组)为(0.35±0.05)mmol/L,冠状动脉双支病变组(2支组)为(0.46±0.07)mmol/L,冠状动脉3支病变组(3支组)为(0.48±0.04)mmol/L,随着病变支数的增加,血尿酸水平也逐渐增加,1支、2支、3支组血尿酸水平与0支组比较差异有显著意义(P<0.05),2支、3支组与1支组比较,血尿酸水平差异有非常显著意义(P<0.01)。结论随着冠状动脉病变程度的增加,血尿酸水平也逐渐增高。 Objective To investigate the correlation between coronary artery lesions and serum uric acid (UA) .Methods The fasting serum UA levels were measured in 64 patients and coronary angiography was used to divide these patients into different groups according to the pathological degree of coronary artery. Results The UA levels of patients with normal coronary, artery (group 0) were (0.30± 0.06)mmol/L, which in patients with one ramus coronary artery pathological change ( group one) was ( 0.35 ± 0.05 ) mmol/L, accordingly, group two and group three were (0.46 ± 0.07)mmol/L and (0.48 ± 0.04)mmol/L respectively. With the increase of ramus number of coronary artery of pathological change, the serum UA levels were increased. There was a significant difference between group one, group two, group three and group 0 ( P 〈 0.05 ), compared with group 1, the UA levels in group 2 and group 3 were significantly higher ( P 〈 0.01).Conclusion The levels of UA are positively correlated with the severity, degree of coronary artery lesion.
出处 《疑难病杂志》 CAS 2007年第6期333-335,共3页 Chinese Journal of Difficult and Complicated Cases
关键词 冠状动脉病变 血尿酸 造影 冠状动脉 Coronary artery pathological change Serum uric acid Angiography, coronary, artery
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  • 1张俊,罗开良,刘增长,高兴玉,吕湛,罗勇,刘丽.高血压肱动脉血流依赖性舒张功能与高尿酸血症的关系[J].临床心血管病杂志,2004,20(7):406-408. 被引量:4
  • 2Ishizaka N, Ishizaka Y, Toda E, et al. Association between serum uric acid, metabolic syndrome, and carotid atherosclerosis in Japanese individuals. Arterioscler Thromb Vasc Biol,2005 ,25:1038-1044.
  • 3Short R A, Johnson R J, Tuttle K R. Uric acid, microalbuminuria and cardiovascular events in high-risk patients. Am J Nephrol, 2005 , 25:36-44.
  • 4Kanellis J, Kang D H. Uric acid as a mediator of endothelial dysfunction, inflammation, and vascular disease. Semin Nephrol, 2005 ,25:39-42.
  • 5朱轼,王汝莲,张廷杰.高尿酸血症与心血管疾病[J].心血管病学进展,1999,20(3):175-177. 被引量:43

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