摘要
目的:观察急性冠状动脉综合征(ACS)患者血清尿酸(UA)、肌钙蛋白I(cTnI)和高敏C反应蛋白(hs-CRP)含量并探讨对其临床预后的预测价值。方法:入选确诊ACS的住院患者592例,收集入院24h内UA、cTnI和hs-CRP的数值,并对患者出院后的心血管事件进行随访,分为心血管事件组和无心血管事件组。结果:UA、cTnI和hs-CRP在2组之间的差异均有统计学意义;校正了年龄、职业、吸烟史、BMI、高血压、糖尿病等相关因素后,血清UA、cTnI和hs-CRP能独立预测ACS患者再发心血管事件。结论:血清UA、cTnI和hs-CRP水平升高与ACS患者的再发心血管事件显著相关,具有较强的预测价值。
Objective：To investigate the level and prognostic value of serum uric acid （UA）, troponin Ⅰ （cTnⅠ） and high sensitive CRP （hs-CRP） in patients with acute coronary syndrome （ACS）. Method：A total of 592 patients with ACS was enrolled in this study. Blood samples were collected within 24 hours after admission for the determination of serum UA, cTnⅠ and hs-CRP. The post discharge cardiovascular events were recorded by which the patients were divided into cardiovascular events group and non-cardiovascular events group. Result： Serum UA, cTnⅠ, and hs-CRP levels were significantly different between two groups. After adjusting the related factors including age, vocation, smoking history, BMI, hypertension, diabetes in logistic regression, serum UA, cTnⅠ and hs- CRP levels had independent predictive values for post discharge cardiovascular events. Conclusion：The levels of serum UA, cTnⅠ and hs-CRP, as prognostic factors, are closely associated with post-discharge cardiovaseular events in patients with ACS.
出处
《临床心血管病杂志》
CSCD
北大核心
2008年第9期665-667,共3页
Journal of Clinical Cardiology
关键词
冠状动脉综合征
预后
尿酸
肌钙蛋白Ⅰ
高敏C反应蛋白
Acute coronary syndrome
Prognosis
Uric acid
Troponin Ⅰ, High-sensitive C reactive protein
