摘要
目的:初步探讨蛇床子素的抗凝血作用。方法:通过测定小鼠凝血时间(CT)、大鼠的凝血酶原时间(PT)和优球蛋白溶解时间(ELT),观测蛇床子素的抗凝作用。结果:与对照组比较,不同浓度的蛇床子素能显著延长CT、PT(P<0.001),缩短ELT(P<0.001)。结论:蛇床子素可延长CT、PT,缩短ELT,具有明确的抗凝血作用。
Objective: To preliminary study the effects of Osthol on anticoagulation. Method: Coagulaton time ( CT), prothrombin time (PT), and englobulin lysis time (ELT) were used to evaluate the anticoaguhation effects of Osthol. Result:It was found that Osthol of various concentrations could significantly delay CT and PT( P 〈 0.01 ), and decrease EIT( P 〈 0.01 ). Conclusion: Osthol can prolong CT and PT, and shorten ELT, indicating its unambiguous effect on blood anticoagulation.
出处
《赣南医学院学报》
2007年第2期173-174,219,共3页
JOURNAL OF GANNAN MEDICAL UNIVERSITY