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先天性人巨细胞病毒感染发病机制的研究进展 被引量：6

Progress in the Pathogenesis of Congenital Human Cytamegalovirus Infection
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摘要 人巨细胞病毒（HCMV）是人类最常见的先天性感染病毒，可引起流产、早产、死胎、胎儿宫内发育迟缓及小头畸形、抽搐、脑瘫、智力低下、视力损害及听力损害等后遗症。目前先天性HCMV感染的发病机制仍处于研究阶段。该文对近年来先天性HCMV感染发病机制的研究报道进行综述，主要涉及HCMV的潜伏．激活；HCMV的致畸机制，包括HCMV的直接损伤、通过影响胎盘和绒毛的损伤而导致胎儿畸形、HCMV感染引起细胞凋亡、同源盒基因表达异常及HCMV感染对脑组织的损伤；HCMV感染对免疫系统功能损害机制。
作者 贺晓日（综述） 陈平洋（审校）
机构地区 中南大学湘雅二医院新生儿科
出处 《国际儿科学杂志》 2007年第3期220-222,共3页 International Journal of Pediatrics
关键词 人巨细胞病毒感染 免疫抑制 感染发病机制
分类号 R745 [医药卫生—神经病学与精神病学]
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参考文献18

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二级参考文献62

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共引文献37

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引证文献6

二级引证文献53

国际儿科学杂志
2007年 第3期

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