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不同剂量布托啡诺剖宫产术后硬膜外镇痛的研究 被引量:5

A study on postoperative epidural analgesia after caesarean section with different dose of butorphanol
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摘要 目的:观察不同剂量布托啡诺剖宫产术后硬膜外镇痛效果。方法:60例(ASAI~Ⅱ级)剖宫产病人随机分成3组,对照组(BM组)、实验组1(B1组)、实验组2(B2组)。镇痛药物为:BM组(n=20)0.1125%布比卡因+0.004%吗啡;B1组(n=20)0.1125%布比卡因+0.004%布托啡诺;B2组0.1125%布比卡因+0.006%布托啡诺。采用负荷量+持续剂量给药模式,持续剂量背景流速3ml/h。结果:①VAS、BCS评分在术后8h,BM组低于B1组,BM组与B2组无明显差异。B1组与B2组各项评分无明显差异。②并发症:各组恶心呕吐、搔痒及呼吸抑制的发生率差异无显著性。结论:0.1125%布比卡因+0.006%布托啡诺剖宫产术后硬膜外镇痛效果确切,但不良反应的发生率与0.1125%布比卡因+0.004%吗啡组相比无明显改善。 To observe the analgesic effects with different dose of butorphanol for postoperative epidural analgesia after caesarean section. Methods: 60 ASA Ⅰ~Ⅱ cases undergone caesarean section were randomly divided into control group(group BM, n = 20, mixture of 0.1125% bupivacaine and 0.004% morphine). No. 1 experimental group(group BI, mixture of 0.1125 % bupivacaine and 0.004% butorphanol) and No. 2 (group B2, n = 20; mixture of 0. 1125% bupiva-caine and 0.006% butorphanol). The three groups were carried out by loading-continuous administration with continuous doses of 3 ml/h by a pump. Results:①VAS and BCS in group BM were lower than that in group BI at 8 h during postoperative with no difference in 132. ②The in-cidence of nausea and pruritus in group BM was equivalent to group B1 or B2. Conclusion: Epidural administration of 0. 1125% bupivacaine and 0. 006% butorphanol will provide analgesia for post-caesarean section, but that produces obvious adverse effects.
出处 《皖南医学院学报》 CAS 2007年第2期144-146,共3页 Journal of Wannan Medical College
关键词 布托啡诺 硬膜外 术后 镇痛 剖宫产 butorphanol epidural postoperation analgesia caesareansection
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参考文献7

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二级参考文献9

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