期刊文献+

炎症标志物抵抗素研究进展 被引量:7

Progress on Inflammatory Marker Resistin
在线阅读 下载PDF
导出
摘要 抵抗素是一种与肥胖以及肥胖相关疾病密切相关的脂肪细胞因子。近年研究表明,该因子参与炎症的发生过程。文章从抵抗素与炎症因子和C反应蛋白的相关性,与内皮细胞的相互作用以及炎症相关的临床和试验研究几个方面阐述了抵抗素与炎症的关系。 Resistin is an adipokine which is related to obesity and associated diseases. However, an increasing number of evidences indicate that this cytokine participates in the establishment of inflammation. In this paper,the research reviewed advances of the relationship between resistin and inflammatory cytokines and C reactive protein,the reciprocal effects of resistin on vascular endothelial ceils and the clinical and experimental evidences.
作者 张望 张健
出处 《动物医学进展》 CSCD 2007年第5期88-90,共3页 Progress In Veterinary Medicine
关键词 抵抗素 表达调控 炎症信号途径 resistin expressional regulation inflammatory signal pathway
  • 相关文献

参考文献16

  • 1Steppan C M,Bailley S T,Bhat S,et al.The hormone resistin links obesity to diabetes[J].Nature,2001,409:307-312.
  • 2Vozarovade C B,Degawa Y M,Considine R V,et al.High serum resistin is associated with an increase in adiposity but not a worsening of insulin resistance in Pima indians[J].Diabetes,2004,53:1279-1284.
  • 3Lee J H,Chan J L,Yiannakouris N,et al.Circulating resistin levels are not associated with obesity or insulin resistance in humans and are not regulated by fasting or leptin administration:cross-sectional and interventional studies in normal,insulin-resistant,and diabetic subjects[J].J Clin Endocrinol Metab,2003,88:4848-4856.
  • 4Stejskal D,Adamovska S,Bartek J,et al.Resistin:concentrations in persons with type 2 diabetes mellitus and in individuals with acute inflammatory disease[J].Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub,2003,147:63-69.
  • 5Bokarewa M,Nagaev I,Dahlberg L,et al.Resistin,an adipokine with potent pro-inflammatory properties[J].J Immunol,2005,174:5789-5795.
  • 6Reilly M P,Lehrke M,Wolfe M L,et al.Resistin is an inflammatory marker of atherosclerosis in humans[J].Circulation,2005,111:932-939.
  • 7Daghri A N,Chetty R,Ternan P G,et al.Serum resistin is associated with C-reactive protein and LDL cholesterol in type 2 diabetes and coronary artery disease in a Saudi population[J].Cardiovasc Diabetol,2005,4:10.
  • 8Kaser S,Kaser A,Sandhofer A,et al.Resistin messengerRNA expression is increased by proinflammatory cytokines in vitro[J].Biochem Biophys Res Commun,2003,309:286-290.
  • 9Shojima N,Sakoda H,Ogihara T,et al.Humoral regulation of resistin expression in 313-L1 an d mouse adipose cells[J].Diabetes,2002,51:1737-1744.
  • 10Bokarewa M,Nagaev I,Dahlberg I,et al.Resistin,an adipokine with potent proinflammatory properties[J].The Journal of Immunology,2005,18:5789-5795.

同被引文献87

引证文献7

二级引证文献38

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部