期刊文献+

186例血液病患者血小板输注临床分析 被引量:10

暂未订购
导出
摘要 目的:对我院186例血液病患者血小板输注的疗效进行回顾分析。方法:根据血小板计数和出血表现等因素将血小板输注分为预防性和治疗性输注,比较不同性质、病因之间血小板输注疗效的差别。结果:预防性和治疗性血小板输注有效率分别为97.7%和80.2%,两者比较差异有统计学意义(P<0.01);血液肿瘤病患者化疗后血小板输注有效率和平均血小板升高值分别为92.4%和15.03×109/L,明显高于特发性血小板减少性紫癜(ITP)患者(86.7%和6.27×109/L),两者比较差异有统计学意义(P<0.05)。结论:血小板输注对伴有血小板减少的血液病患者有显著疗效,预防性输注疗效明显优于治疗性输注;血液肿瘤病患者化疗后的血小板输注疗效明显优于ITP患者;血小板输注治疗应做到个体化。
出处 《临床血液学杂志》 CAS 2007年第3期167-170,共4页 Journal of Clinical Hematology
  • 相关文献

参考文献16

  • 1STANWORTH S J,HYDE C,HEDDLE N,et al.Prophylactic platelet transfusion for haemorrhage after chemotherapy and stem cell transplantation[J].Cochrane Database Syst Rev,2004,18:CD004269.
  • 2PISCIOTTO P T,BENSON K,HUME H,et al.Prophylactic versus therapeutic platelet transfusion practices in hematology and/or oncology patients[J].Transfusion,1995,35:498-502.
  • 3郭庆东,戴月娥,穆士杰,傅菊芳,张献清,夏爱军,郑岩.血小板输注治疗血液病患者79例的效果[J].第四军医大学学报,2002,23(7):651-652. 被引量:27
  • 4汪传喜,田兆嵩.血小板输注的现状与展望[J].中国输血杂志,2000,13(4):280-283. 被引量:79
  • 5HIGBY D J,COHEN E,HOLLAND J F,et al.The prophylactic treatment of thrombocytopenic leukemic patients with platelets:a double blind study[J].Transfusion,1974,14:440-446.
  • 6ROY A J,JAFFE N,DJERASSI I.Prophylatic platelet transfusions in children with acute leukemia:a dose response study[J].Transfusion,1973,13:283-290.
  • 7陈江声,杨燕娇.血小板输注对慢性ITP伴明显出血的疗效观察[J].河北医学,2005,11(1):41-43. 被引量:4
  • 8GAYDOS L A,FREIREICH E J,MANTEL N.The quantitative relation between platelet count and hemorrhage in patients with acute leukemia[J].N Engl J Med,1962,266:905-909.
  • 9NEVO S,ENGER C,HARTLEY E,et al.Acute bleeding and thrombocytopenia after bone marrow transplantation[J].Bone Marrow Transplant,2001,27:65-72.
  • 10CALLOW C R,SWINDELL R,RANDALL W,et al.The frequency of bleeding complications in patients with haematological malignancy following the introduction of a stringent prophylactic platelet transfusion policy[J].Br J Haematol,2002,118:677-682.

二级参考文献8

  • 1陈江声,杨燕娇,刘峰.血小板输注对慢性原发性血小板减少性紫癜的作用[J].实用医学杂志,2004,20(5):535-536. 被引量:3
  • 2[1]Williamson LM,Wimperis JZ,Williamson P.Bedside filtration of blood products in the prevention of HLA-alloimmunization [J].Blood,1999;84:3078-3079.
  • 3[2]Sichter SJ.The trail to reduce alloimmunization to prevent alloimmuniza [J].N Engl J Med,1997;337:1861.
  • 4[3]Chun HY.Prospects For the platelet transfusion [J].Clin Blood,1998;39(2):78-79.
  • 5[4]Kevin D,Heckman,George J.Randomized Study of proghylatic transfusion threshold during induction therapy for adult platelet acute Leakemia:1000/μl vs 2000/μl [J].J Clin Oncol,1997;15(3):1143-1149.
  • 6Nagasawa T Kim BK,Baldini MG:Temporary suppression of circulating antiplatelet alloantibodies by the massive infusion of fresh,stored or lyophilized platelets[J].Transfusion,1978,18:429.
  • 7杨天楹 杨成民 田兆嵩 主编.临床血液学[M].北京:北京医科大学、中国协和医科大学联合出版社,1993.257.
  • 8陈澍英,肖露露,邹小立,佘妙容,林伟,叶欣,林惠群,马琳雅,陈江声.组织相容性抗原与血液病患者反复输注血小板效果的相关性[J].中华医学杂志,1998,78(11):824-826. 被引量:16

共引文献105

同被引文献77

引证文献10

二级引证文献39

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部