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紫杉醇治疗中晚期胃癌的疗效观察 被引量:1

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摘要 目的探讨紫杉醇联合化疗在中晚期胃癌治疗中的疗效及不良反应。方法对58例中晚期胃癌患者给予紫杉醇加顺铂加5-氟脲嘧啶和醛氢叶酸联合化疗。紫杉醇135—175mg/m^2,静脉滴注,第1天;顺铂30mg/m^2,静脉滴注,第2—4天,醛氢叶酸200mg/m^2,静脉滴注,第2—3天;5-氟脲嘧啶400mg/m^2,静脉滴注,第2天,600mg/m^2泵入22h,第2—3天。结果有效率53.4%,大于以往的化疗方案有效率(30%~40%)。中位生存期9~11个月;大于以往化疗方案的病人中位生存期3—5个月。中位疾病进展时间6.1个月;大于以往化疗方案的病人中位疾病进展时间5个月。结论紫杉醇联合顺铂对中晚期胃癌进行化疗,有效率高,中位生存期及中位疾病进展时间延长,不良反应在一般患者可耐受范围内。
出处 《中原医刊》 2007年第8期76-77,共2页 Central Plains Medical Journal
关键词 紫杉醇 胃癌 治疗
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参考文献5

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