摘要
分次照射是研究辐射损伤修复的重要途径之一。本文报道用修复抑制剂咖啡因预处理后用X射线单次或分次照射小麦或大麦萌发种子,来研究咖啡因对潜在致死损伤修复和亚致死损伤修复的作用。和别的作者的结果不同,咖啡因既能抑制潜在致死损伤的修复又能抑制亚致死损伤的修复。根据本文的实验结果,讨论了分次照射中间歇期间的修复效率以及照射结束后的修复过程。
Fractionated irradiation is one of the important methods studyingrepair of radiation damage. Some authors reported that caffeine, a repair inhibitor.had no effects on fractionated irradiation in human cell. animal cell and Vicia faba.And they concluded that caffeine inhibited the repair of potentially lethal damage(PLD), but did not inhibit the repair of sub-lethal damage (SLD). In this study, theeffect of caffeine on the repair of PLD and SLD were reexamined in wheat and bar-ley systems. The germinating seeds of wheat of barley were pre-irradiation treated 3 hwith 5×10^(-3) mol/L caffeine, then they were irradiated by single or fractionated X-ray doses. The results showed that after caffeine treatment the effect of fractionatedirradiation was disappeared. In this case, caffeine not only inhibited the repair of PLDbut also inhibited the repair SLD. In previous fracttionated radiation experiments, the repairs during interval werediscussed in detail. but the repairs after whole irradiation were neglected. Accordingto the results of this experiment and some early reports about fractionated irradiation,the repair efficiency during interval and the repair function after whole irradiationwere discussed.
出处
《辐射研究与辐射工艺学报》
CAS
CSCD
北大核心
1990年第3期159-162,共4页
Journal of Radiation Research and Radiation Processing
基金
国家自然科学基金
关键词
照射
咖啡因
小麦
大麦
修复
Fractionated irradiation
Caffeine
Sub-lethal damage
Potentially lethal damage
Repair
Wheat and barley
