摘要
报告经腹腔镜ＣＯ２激光卵巢打孔治疗难治性多囊卵巢综合征（ＰＣＯＤ）２０例。术后８例患者自然排卵，１１例患者用克罗米芬治疗有排卵。８例患者术后妊娠，１例孕６周自然流产，７例目前在妊娠中，妊娠率为４０％。流产率为１２．５％。术后血中睾酮及促黄体生成素（ＬＨ）浓度明显下降，而促卵泡生成素（ＦＳＨ）浓度改变不明显。术后激素环境改变是诱发排卵的主要机理。ＣＯ２激光具有作用部位准确，组织破坏程度易控制及手术野无出血等优点。本治疗具有损伤小，恢复快的特点。一次治疗可获多个排卵周期，无多胎妊娠及卵巢过度刺激综合征等合并症，是治疗难治性ＰＣＯＤ的有效方法。
Twenty anovulatory women with clomiphene citrate(CC) resistant polycystic ovarian disease were treated laparoscopically by CO 2 laser vaporization. Ovulation occurred spontaneously postoperatively in 40%. 11 patients responded to CC postoperatively. 8 women conceived after operation. This include 1 case of spontaneous ovulator and 7 cases of postoperative CC stimulated. One pregnancy aborted spontanously at 6 weeks gestation. The remain 7 cases are on going singleton pregnancy. The pregnancy rate is 40% and the abortion rate is 12.5%. The mechanism by which ovarian laser vaporization restore ovarian function is the reduction of androgen and luteinizing hormone concentration. CO 2 laser has the characteristics of precise effect, easy control and minimal bleeding. Ovarian CO 2 laser vaporization through laparoscopy is a minimal invasive operation. One treatment can produce multiple ovulatory cycles. It can avoid multiple pregnancy and ovarian hyperstimulation syndrome. It is an effective method for the treatment of refractory polycystic ovarian disease.
出处
《中山医科大学学报》
CSCD
1997年第1期68-70,共3页
Academic Journal of Sun Yat-sen University of Medical Sciences
关键词
多囊卵巢
综合征
腹腔镜
激光手术
polycystic ovary syndrome/therapy
surgery, laparscopy
laser surgery
