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麻风免疫中IL-12及其受体的研究进展 被引量：1

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摘要 抗麻风菌免疫主要依赖保护性细胞免疫(Cell-Mediated Immunity,CMI)的建立,而选择性诱导Th1细胞分化是建立CMI的关键。在抗感染先天性免疫,IL-12是介导先天性免疫和决定适应性免疫发展的枢纽。本文对IL-12的结构、生物学功能、产生和调节,IL-12受体的生物学功能,体外IL-12及其受体表达的调节,IL-12及其受体在麻风保护性免疫中的作用等方面的研究进展作了综述。
作者 陈小华 翁小满
机构地区 首都医科大学附属北京友谊医院北京热带医学研究所
出处 《中国麻风皮肤病杂志》 2007年第4期325-328,共4页 China Journal of Leprosy and Skin Diseases
关键词 麻风 IL-12 IL-12受体 免疫
分类号 R755 [医药卫生—皮肤病学与性病学] R392 [医药卫生—免疫学]
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同被引文献17

  • 1李继红,崔茜,张锦.麻风易感人群NK细胞活性的检测[J].中国热带医学,2004,4(6):1044-1045. 被引量：2
  • 2翁小满,胡永秀.麻风病免疫中的树突状细胞与T细胞的相互作用及其研究进展[J].中国麻风皮肤病杂志,2005,21(3):200-203. 被引量：2
  • 3李桓英.麻风病研究进展[J].中国麻风皮肤病杂志,2006,22(10):846-848. 被引量：5
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中国麻风皮肤病杂志
2007年 第4期

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