摘要
目的:探讨药物所致过敏性休克死亡的特点、规律及相关危险因素。方法:检索中文医药卫生期刊1998～2006年报道的药源性过敏性休克死亡个案病例,并对文献资料进行整理、汇总和分析。结果:老年人和儿童发生比例较高;抗感染药物、中药制剂、酶类及其它生物制剂的过敏性休克死亡率居前3位。静脉给药发生率最高,占69.64%,速发型过敏性休克死亡比例最大,占73.21%。结论:药物所致过敏性休克死亡与患者年龄、用药时间、药物特点及给药途径等有关。
Objective： To investigate the characteristics, regularities and risk factors of the fatal druginduced anaphylactic shock. Methods： The fatal cases of drug-induced allergic shock, published on Chinese medical periodicals during the period of 1998 to 2006, were collected and analyzed. Results： The mortality of allergic shock induced by anti-infective agents, traditional Chinese medicine preparations and biologics occupied the top 3 places in sequence, and the shock induced by intravenous administration occupied the first place （69.64%）. Most of death was immediate allergy type （73.21%）. Conclusion： There are relations between the mortality and age, administration time, characteristics of drugs and administration route.
出处
《天津医科大学学报》
2007年第1期26-28,共3页
Journal of Tianjin Medical University
关键词
药物过敏性休克
死亡
文献分析
Drug-induced anaphylactic shock
Death
Literature analysis
