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有机胂添加剂对蛋白核小球藻及大型蚤的急性毒性研究 被引量:4

Studies on Acute Toxicity of Organoarsenics to Chlorella pyrenoidosa and Deaphnia magna
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摘要 为评估有机胂添加剂对水环境的影响,以蛋白核小球藻、大型蚤为研究对象,研究了洛克沙胂、阿散酸对蛋白核小球藻和大型蚤的急性毒性.结果表明:洛克沙胂、阿散酸对蛋白核小球藻的24、48、72、96 h的半数有效抑制浓度(EC50)分别为:190.55、263.03、346.74、389.05 mg.L-1;239.88、308.18、418.12、410.40 mg.L-1(以原型药物计);均大于100 mg.L-1,在水环境中为低毒级化合物(急性Ⅲ化学物质以下).对大型蚤24 h-EC50分别是49.77、83.70 mg.L-1;48 h-EC50分别是39.00、57.48 mg.L-1,48 h-LC50分别是44.19、61.97 mg.L-1(均以原型药物计);依据蚤类急性活动抑制毒性分级标准,它们属于中毒级化合物. In order to evaluate impact of organoarsenics on aquatic system, the acute toxicity of organo-arsenics to Chlorella pyrenoidosa and Deaphnia magna was examined in this study. The 24, 48, 72, 96 h-EC50( effective concentration for 50% reduction in growth) of roxarsone and arsanilic acid to C. pyrenoidosa was 190. 55,263. 03,346. 74, 389.05 mg · L^-1, and 239. 88、308. 18、418. 12、410. 40 mg · L^-1 (present as archetypal compound), respectively, which were all more than 100 mg · L^-1, so the two organoarsenical compounds had low toxicity to C. pyrenoidosa. The 24 h-EC50 of roxarsone and arsanilic acid to D. magna was 49. 77,83.70 mg · L^-1 ( present as archetypal compound), respectively. The 48 h-LC50 ( lethal concentration for 50 % ) of the two compounds to D. magna was 44. 19, 61.97 mg · L^- 1 ( present as archetypal compound), respectively, and that of the 48 h-EC50 was 39. 00, 57.48 mg· L^-1 , respectively. According to toxicity standard to D. magna, the two compounds were median toxic to D. magna.
出处 《华南农业大学学报》 CAS CSCD 北大核心 2007年第2期103-106,共4页 Journal of South China Agricultural University
基金 国家自然科学基金重点资助项目(30130140)
关键词 有机胂添加剂 蛋白核小球藻 大型蚤 急性毒性 organoarsenics Chlorella pyrenoidosa Deaphnia magna acute toxicity
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参考文献15

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