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DNA甲基化与胚胎发育的研究进展 被引量:5

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摘要 DNA甲基化指DNA序列不发生变化但基因表达却发生了可遗传的改变,这种改变在胚胎发育和细胞增殖过程中能稳定传递,其在干细胞发育或早期胚胎形成时就建立。DNA甲基化模式的改变是胚胎发育的关键,其通过基因沉默、印迹清除和重建、X染色体失活等作用于胚胎发育期。对近年DNA甲基化在胚胎发育过程中作用的研究进行综述。
出处 《国外医学(妇产科学分册)》 2007年第1期8-11,共4页 Foreign Medical Sciences(Obstet Gynecol Fascicle)
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