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苯对作业工人血清SOD活性影响的观察 被引量:11

OBSERVATION ON EFFECT OF BENZENE ON SERA SOD' S ACTIVITIES OF EXPOSED WORKERS
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摘要 根据作业环境条件选择130名工人,分为对照组、低浓度接触组和高浓度接触组,同时将25名轻度苯中毒工人列为中毒组。常规方法进行周围血白细胞计数,并对血清中SOD活性进行测定,结果表明:苯中毒组白细胞数明显低于其它三组,血清SOD活性高于对照组,SOD活性与白细胞数呈负相关,可能因长期接触高浓度苯且反应敏感者体内自由基增多。 According to the working environment 130 workers were divided into control group, low con centration group, and high concentration group. And 25 intoxicated workers were taken as the ben zene intoxicated group. white blood cells of workers were routinely counted. At the same time the activities of sera SOD were detected. It was showed that the numbr of WBC in benzene intoxicated group was lower than those in other three groups, while the activities of SOD in benzene intoxicat ed group were higher than those in control group. Negative correlationship existed between the WBC count and the activities of SOD. These results indicated that more radicals were formed in the into xicated workers chronically exposed to bigh concentration benzene who were allergic to Benzene.
出处 《工业卫生与职业病》 CAS CSCD 1996年第2期86-88,共3页 Industrial Health and Occupational Diseases
基金 国家自然科学基金
关键词 苯中毒 血清SOD Benzene exposure Benzene poisoning Sera SOD
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参考文献3

  • 1薛玉凤.超氧化物歧化酶的测定及其临床意义[J].河北医药,1990,12(2):109-110. 被引量:8
  • 2翁其亮,万田郎,苏祖佑,曹容珍.自由基■水平与人的血癌——■相对含量的间接测定[J]生物化学与生物物理进展,1986(03).
  • 3林兴成,章瑜,王沙史.急性苯中毒对小鼠骨髓细胞的影响及SOD的保护作用[J]工业卫生与职业病,1984(02).

二级参考文献1

  • 1丁克祥,钟水先,姚树人.微量指血超氧化物歧化酶快速测定法的研究[J]老年学杂志,1987(02).

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