摘要
目的观察灭滴灵加蒙脱石散剂用于治疗慢性阻塞性肺病病人口腔黏膜炎的临床效果。方法将78例发生口腔黏膜炎的慢性阻塞性肺病病人随机分为AB两组各39例,均先用生理盐水清洁口腔,A组以0.5%灭滴灵溶液作漱口液进行口腔护理,再将蒙脱石散剂以棉棒蘸之,均匀撒附在黏膜红肿溃烂处;B组用蒙脱石散剂直接涂于黏膜红肿溃烂处,比较两组口腔黏膜炎的愈合情况及愈合的时间。结果A组治疗有效率为97.4%,B组治疗有效率为94.9%,两组比较,差异有统计学意义(P<0.05),A组效果优于B组。两组在恢复进食时间和愈合时间上比较,差异有统计学意义(均P<0.05),A组时间明显短于B组。结论先以灭滴灵漱口液进行口腔护理,再局部配合外涂蒙脱石散剂治疗慢性阻塞性肺病病人口腔黏膜炎,效果好,值得临床推广应用。
Objective To investigate the effect of metronidazole combined with smectite powder on the oral mucositis of patients with chronic obstructive pulmonary disease （COPD） at department of respiratory diseases. Methods 78 COPD patients with oral mucositis at department of respiratory diseases were equally randomized into two groups： group A and group B. After oral cavity was cleaned by norwal saline for all the eases, 0. 5% metronidazole gargle was applied in oral nursing, and then, mucoses ulcer was covered with smeetite powder in group A; while in group B, the method was the same as the group A, besides oral care with metronidazole gargle. At last, clinical effects between two groups were compared. Results Time for resuming to diets and getting recovered in group A was significantly shorter than that in group B （ P 〈 0.05 ）. Conclusion Metronidazole gargle combined with smectine powder deserves extensive use in treatment of patients with oral mucositis at department of respiratory diseases.
出处
《现代临床护理》
2007年第1期36-37,共2页
Modern Clinical Nursing
关键词
口腔黏膜炎
灭滴灵
蒙脱石散剂
慢性阻塞性肺病
oral mucositis
metronidazole
smecfite powder
chronic obstructive pulmonary disease
