摘要
目的:了解淮安市新生儿苯丙酮尿症(PKU)的发病情况。方法:在新生儿出生72h并充分哺乳后,采集足跟血制成滤纸血片,应用荧光测定法测定血片中苯丙氨酸的浓度。结果:从2002年3月～2004年底,在淮安市42483名新生儿中共筛查出苯丙酮尿症患儿10例,新生儿PKU的发病率为1∶4248。结论:在新生儿疾病筛查工作中,要重视筛查工作的质量,逐步提高筛查覆盖率,提高淮安市儿童保健水平。
ObJective： To realize incidence of phenylketonuria in Huaian. Methods： Sample of heel blood collected from newborn after 72 hours, and dropped on stipulated filter paper to determine the phe concentration of blood according to fiuorometric methods. Results： From 2002 to 2004 in Huaian, totally of 42 483 newborns were screened for PKU, 10 cases of PKU detected with an incidence of 1 ： 4 248. Conclusion： In development of neonatal screening, it is necessary to attach more impertanee to quality of screening and gradual increasing coverage of screening, improvement of level of child health care in Huaian.
出处
《中国妇幼保健》
CAS
北大核心
2007年第7期902-903,共2页
Maternal and Child Health Care of China
关键词
新生儿筛查
苯丙酮尿症
荧光测定法
Neonatal screening
Phenylketonuria
Fluorometric method
