摘要
目的分析根尖囊肿衬里上皮细胞增殖及其与郎格罕细胞分布的关系。方法收集23例经组织病理学确诊的根尖囊肿石蜡标本,分别进行增殖细胞标记Ki-67和郎格罕细胞标记S-100的免疫组化染色,观察根尖囊肿衬里上皮的细胞增殖及其与郎格罕细胞分布的关系。结果衬里上皮内的Ki-67阳性的细胞数目与结缔组织囊壁内的S-100阳性的细胞数目呈正相关(P<0.05),但与衬里上皮内的S-100阳性的细胞数目无相关关系(P>0.05)。结论结缔组织囊壁中的郎格罕细胞数目与衬里上皮的增殖活性呈正相关,提示囊壁内由郎格罕细胞参与介导的免疫反应可能有促进上皮增殖的作用。
Objective To analyze the relation between the proliferation of epithelial lining cell and the distribution of Langerhans' cell in radicular cysts. Methods 23 examples of radicular cysts were immunohistochemically analyzed for the distribution of Langerhans, cell and proliferative activity as indicated by positivity for S- 100 and Ki - 67 respectively. Results The number of Ki - 67^+ ceils in epithelial lining is related to that of S - 100^+ cells in cyst wall( P 〈0.05), however, there is no correlation between Ki - 67^+ cells and S- 100^+ cells in epithelial lining ( P 〉0.05). Conclusion The immune responses induced by Langerhans, cell in cyst wall perhaps can accelerate the proliferation of epithelia.
出处
《现代口腔医学杂志》
CAS
CSCD
北大核心
2007年第2期138-140,共3页
Journal of Modern Stomatology
关键词
根尖囊肿
郎格罕细胞
Radicular cysts Langerhans' cell