摘要
目的探讨不同手术方式对胃肠道间质瘤(GIST)复发及预后的影响。方法回顾性分析我科8年来收治的GIST患者临床资料,根据手术方式不同分为两组,A组为行肿瘤局部切除术者14例,B组为行肿瘤所在器官大部分切除、全切或包括淋巴结清扫的扩大切除术者12例,对两组病例进行随访,分别计算中位生存期、1年、2年和5年生存率、复发率,并对两组数据进行比较。结果A组14例中13例获得随访,中位生存时间36个月,B组12例均获得随访,中位生存时间40个月,两组比较,P>0.05;A组1年、2年和5年生存率分别为92.3%、85.4%和69.2%,B组1年、2年和5年生存率分别为91.7%、83.3%和66.7%,两组比较,P>0.05。说明两组手术对患者生存时间的影响无统计学意义。A组术后出现复发和转移2例,占14.3%,B组术后出现复发和转移2例,占16.7%,两组比较,P>0.05,说明两种手术方式对复发和转移率的影响无统计学意义。结论手术切除是治疗GIST的最好方法,只要肿瘤完整切除,采用局部切除或扩大切除对术后复发和转移影响不大。
Objective To evaluate the effect of different surgical treatments on relapse and prognosis of patients with gastrointestinal stromal turrets （GIST）. Methods Clinical data of patients with GIST during recent 8 years were reviewed retrospectively. Twenty - six cases were grouped according to surgical procedures： local resecfon （group A,14 cases）; organ or enlarged resection （group B,12 cases）. Median survival time,survival and recurrence rate were calculated and compared. Results Thirteen cases in group A and all patients in group B were followed up,median survival time was 36 months and 40 months respectivdy （ P 〉 0.05 ）. Survival rate of 1 - year,2 - year,5 - year was 92.3% ,85.4% ,69.2% respectively in group A,compared to 91.7% ,83.3% ,66.7% in group B （ P 〉0.05）. Relalr, e and metastasis occurred in 14.3% of group A （2/14） compared to 16.7% in group B （2/12） （ P 〉 0.05）. Conclusion Surgical resection is the best way for patients with GIST, there is little effect on relapse ＆ metastasis rate after local resection or enlarged resection if complete gross resection was performed.
出处
《临床外科杂志》
2007年第3期181-183,共3页
Journal of Clinical Surgery
关键词
胃肠道肿瘤
间质瘤
外科治疗
复发
预后
gastroenterie tumor
interstitialoma
surgical treatment
relapse
prognosis
