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EZH2与泌尿系肿瘤 被引量:3

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摘要 人类PCG(Potyeomb Group)基因家族在胚胎发育、细胞周期和血细胞生成调节中起关键性作用。近年来,EZH2基因作为果蝇zeste基因增强子[E(z)]的人类同源物在国内外受到了广泛关注。它属于PCG家族成员之一,是一种基因转录抑制因子,参与细胞记忆的控制。最近研究发现,与前列腺癌、膀胱肿瘤的发生发展有一定关系。本文将就EZH2基因与PCG家族的结构、功能以及与各种肿瘤,特别是泌尿系肿瘤的关系作一综述。
出处 《国际泌尿系统杂志》 2007年第2期219-222,共4页 International Journal of Urology and Nephrology
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同被引文献41

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