摘要
目的探讨急性百草枯中毒患者血清肌酸激酶MB(CK-MB)与预后的关系。方法急性百草枯中毒患者41例,以住院死亡为观察终点分为死亡组和存活组。采用酶法测定中毒后24小时内CK-MB的血清含量并进行统计分析。结果血清CK-MB增高的35例患者,病死率77.14%。死亡组CK-MB显著高于存活组。结论CK-MB在百草枯中毒24小时内明显增高的患者病情重,病死率高,预后差。早期动态监测CK-MB能客观评估病情程度及预后。
Objective To study the correlation between serum level of ereatine kinase of MB type （CK-MB） and prognosis in acute paxaquat-poisoned patients. Methods 41 patients with acute paraquat poisoning were divided into 2 groups ：death group and survival group. The final clinical outcome was defined as either death or survival in hospital. The serum level of CK-MB at 24 h after poisoning was detected by kinase method and analyzed by statistics. Results Mortality rate of 35 patients with elevated serum CK-MB was 77.14% （27 of 35）. The serum level of CK-MB was significantly higher in death group than in survival group（P〈0.05）. Conclusion Acute paraquat-poisioned patients with elevated serum CK-MB often predict a severe status, poor prognosis,and high mortality rate.
出处
《西部医学》
2007年第2期224-225,共2页
Medical Journal of West China
