摘要
目的:确定欣脑泰滴丸成型工艺。方法:以滴丸的硬度,外观,黏连为评价指标,采用正交试验法研究滴丸成型工艺的较优工艺条件。结果:确定工艺为:药物与基质比例为1:3,PEG4000与PEG6000比例为1:1,料温85℃,滴距为5cm。结论:通过上述试验确定的成型工艺合理,所制滴丸符合滴丸质量标准。
Objective： To optimize the preparation procedure of Xinnaotai dropping pills. Methods： All the procedures were evaluated for the hardness, appearance and stickiness of the pills, and optimized by orthogonal design. Results： preparation process of Xinnaotai dropping pill has been optimized that the mixture of extraction of Gingko biloba leaves, Acanthopanax and Gensing leaves and stalk is added into the fused host containing PEG4000 and PEG6000（1：3）, mixed and decanted into dropping pill machine at 8512, then is dropped into fluid wax at the dropping distance of 5cm. Cool and solidify into pills. Conclusion： The optimized process is suitable for the preparation for dropping pills.
出处
《黑龙江医药》
CAS
2007年第2期132-134,共3页
Heilongjiang Medicine journal
基金
本课题为黑龙江省研究生科研创新资金项目(项目编号:YJSCX2005-152HLJ)
关键词
欣脑泰滴丸
成型工艺
正交试验
Xirmaotai Drop Pill
prparation techniques
orthogonal design
