4Paul Willner. Validity.reliability and utility of the chronic mild stress model of depresaion: a 10 - year review and evaluation.Psychopharmacology, 1997,134: 319 ~ 329.
5Gal Yadid, Rachel Nakash,Llana Deri, et al. Elucidation of the neurobiology of depression: insights from a novel genetic animal model. Progress in Neumbiology,2000,62:353 ~ 378.
6Paolo Stefano D' Aquila, Maria Collu, et al. The role of dopamine in the raechanism of action of antidepressant drags. European Journal of Parmacology, 2000,405:365 ~ 373.
7Detawaerdere,P. ,Stinus,L. Opposite change of in vivo dopamine release in the rat nucleus accumbens and striaaan that follows electrical stimulation of dorsal raphe nucleus: role of 5-HT3 receptors. J.Neurosci, 1998,18: 6528 ~ 6538.
8王永炎.中医内科学[M].上海:上海科学技术出版社,1998.274.
9Blows WT. The neurobiology of antidepressants. J Neurosci Nurs,2000,32(3): 177-180
10Nemeroff, Charles B. The Neurobiology of Depression. Scientific American, 1998, 278(6):42-49
2Kessler R C,Berglund P,Demler O,et al.Lifetimeprevalence and age-of-onset distributions of DSM-IVdisorders in the National Comorbidity Survey Replication[J].Arch Gen Psychiatry,2005,62(6):593.
3Yamada M,Higuchi T.Functional genomics anddepression research:beyond the monoamine hypothesis[J].Eur Neuropsychophamacol,2002,12(3):235.
4Grippo A J,Johnson A K.Biological mechanisms in therelationship between depression and heart disease[J].Neurosci Biobehav Rev,2002,26(8):941.
5Takeuchi H,Yatsugi S,Hatanaka K,et al.Pharmacological studies on YM992,a novelantisepressant with selective serotonin re-uptakeinhibitory and 5-HT2A receptor antagonistic activity[J].Eur J Pharmacol,1997,329(1):27.
6David L,Willins,Herbert Y,et al.Direct injection of5-HT2A receptor agonists into the medial prefrontalcortex produces a head-twitch response in rats[J].JPharmacol Ther,1997,282(2):699.
7Goodwin G M,Green A R,Johnson P.5-HT2 receptorcharacteristics in frontal cortex and 5-HT2 receptor-mediated head-twitch behavior following antidepressanttreatment to mice[J].Br J Pharmac,1984,83(1):235.
8Joo P S G,Henk V R,Hemmie H G,et al.A set ofbehaviour altests predicticting and antidepressant aetivity[J].Drug Dev Res,1985,5(2):291.
9Malik J B.Potentiation of yohimbine-induced lethality inmice:Predictor of antidepressant protential[J].DrugDevelop Res,1983,3(4):357.
10Willner P.Chronic mild stress(CMS)revisited:consistency and behavioural-neurobiological concordancein the effects of CMS[J].Neuropsychobiology,2005,52(2):90.
