摘要
本文报告5例6支动脉阻塞经导管使用微量泵持续灌注尿激酶(56,000单位/小时)溶栓治疗,灌注时间5.5～.58(平均26)小时。阻塞位于髂外动脉2例,其中1例伴同侧股动脉阻塞:髂总和髂外动脉联合受累1例,腘动脉1例;股腘动脉1例。病程1～24(平均9.4)个月,阻塞长度8～25cm(平均15.3cm),开通率达100％。对溶栓后残存狭窄实施PTA3例、血管内放置支架1例:随访2～9(平均5.3)个月,临床效果满意。表明溶栓及介入技术联合治疗应作为治疗外周动脉梗阻性病变的首选方法。本文着重讨论小剂量溶栓方法、技术操作、影响因素、综合治疗原则及远期疗效巩固等。
Local low-dose thrombolysis, combined with angioplasty or stent implantation, was performed in 5 patients with chronic occlusions of iliac and femoropopliteal arteries. The obstructed segments were found in the external iliac artery (n=2), common iliac and external artery (n=1), femoral artery (n=1), popliteal artery (n=1) and femoropopliteal artery (n=1). The occluded length ranged from 8～25 (mean, 15.3)cm. The estimated duration of occlusions were from 1～24(mean, 9.4) months. Local thrombolysis was performed by using urokinase 56, 000 IU/h, accompanied by heparin treatment (1,000 IU/h) in all patients. The infusion time ranged from 5.5～58(mean, 26) hours. PTA (n=3) and intravascular stent placement (n=1) were immediately performed after thrombolysis. The initial success rate was 100%. Follow-up lasted 2～9 months (mean 5.3 months). This approach was even succesful in a patient with occluded duration up to 2 years. This therapy represents a true altermative to vascular surgery and as first-choice treatment for segmental peripheral occlusions. Thrombolytic procedure dose, interventional indications, other factors and long-term effects were discussed.
出处
《介入放射学杂志》
CSCD
1996年第4期192-196,共5页
Journal of Interventional Radiology
关键词
外周动脉阻塞
尿激酶
血管内支架
溶栓疗法
Peripheral arterial obstruction
Thrombolysis
Urokinase
Parcutaneous Transluminal angioplasty
Stent and Prostheses
