摘要
目的：探讨血管内局部溶栓的疗效及影响因素。材料与方法：对２０例血管阻塞性病变进行大剂量（４０００ＩＵ／ｍｉｎ）和短时间（平均３．１小时）血管内局部灌注溶栓。结果：阻塞血管完全或部分开通１６例（８０％），无一例并发症发生。结论：作者强调将溶栓导管插入血栓内注射尿激酶，通过增加局部溶栓剂浓度以及溶栓剂与血栓间的接触面可提高再通率。此外，溶栓术后继续抗栓抗凝可增强疗效。血管内局部溶栓治疗血栓栓塞性病变安全而有效，其疗效与多种影响因素有关。
Purpose:Toinvestigatetheinfluencingfactorsandtherapeuticefectofintravascularregionalthrombolysis.MaterialsandMethods:High-dose(4000IU/min)andshortterm(mean,3.1h)ofurokinasewereusedin20caseswiththromboembolicocclusingofvessel.Results:Com-pleteorpartialrecanalizationoftheoclusedveselswerefoundin16cases(80%)withoutcomplica-tioninanycases.Theauthorsemphasizedinsertingthecatheterintothethrombustoinjecturokinasetoincreaserecanalizationrateresultingfromincreasedconcentrationofthrombolyticagentandin-creasedcontactbetweenthethrombusandthethrombolyticagent.Conclusion:Intravascularregion-althrombolysisisanefectiveandsafetreatmentforthromboembolicocclusionofvesselandtheef-fectisrelatedtomanyinfluuencingfactors.
出处
《中华放射学杂志》
CAS
CSCD
北大核心
1996年第2期105-108,共4页
Chinese Journal of Radiology
