摘要
目的通过对3类切口手术患者围手术期抗菌药物使用的调查分析,评估其合理性,增强临床医生的合理用药水平。方法采用限定日剂量(DDD)、药物利用指数(DUI)及住院天数、药品费用等指标,分析围手术期患者抗菌药物的利用情况。结果3类切口手术抗菌药物使用率都>95%,Ⅰ类切口联合用药率为71.6%,76.9%的抗菌药DUI≤1;Ⅱ类切口联合用药率为89.6%,有60.0%的抗菌药DUI≤1;Ⅲ类切口联合用药率为89.6%,仅33.3%的抗菌药符合DUI≤1。3类手术切口中,使用率最高的均为头孢呋辛,其次为依替米星。术后用药时间超过围手术期要求的病例达80.0%。结论围手术期抗菌药物不合理用药现象严重,医师在选用药物时应考虑手术类型、适应证及药物相互作用等因素,加强合理用药意识,提高合理用药率。
Objective To evaluate the rationality and improve the rational elinieal use of antibaeterials by investigation and analysis of the drug in the treatment of perioperative patients of three different styles. Methods The antibaeterials used in perioperative period were analysed in respect to defined daily dose（DDD） ,drug utilization index （DUI） ,the cost of drugs, and the days of hospital ization. Results The rate of antibiotie usage of all the perioperative styles was more than 95%. Style Ⅰ of the perioperative ineision ：71.6% of the reeipes adopted several drugs,76.9% of the antibaeterials with a DUI ≤ 1. Style Ⅱ of the perioperative ineision ：89.6% of the reeipes adopted several drugs ,60.0% of the antibaeterials with a DUI ≤ 1. Style Ⅲ of the perioperative ineision：89.6% of the reeipes adopt several drugs,but only 33.3% of antibaeterials with a DUI ≤1. In all the three types of operation, the highest application rate of antibiotics was eefuroxime, and the second one was etimiein sulfate. More than 80.0% antibioties using after operation is beyond the preseriptive time. Conclusion The phenonmenon of unreasonable application of antibaeterials in perioperative period is very serious. Doctors should pay more attention to such factors as drug interaetion,doses of indieation, and styles of operation , ere in the ehoiee of drug administration and strengthen the level of synthetical management and improve the rate of rational use of drugs.
出处
《医药导报》
CAS
2007年第3期304-307,共4页
Herald of Medicine
关键词
抗菌药
围手术期
合理用药
Antibacterial agents
Perioperative time
Rationality research
