摘要
[目的]评价体外受精-胚胎移植（IVF—ET）后12～14d血清β-HCG对妊娠结局的预测价值。[方法]回顾性分析我院行IVF—ET后妊娠的220例妊娠患者ET后12～14d血清β—HCG与妊娠结局的关系。[结果]血清β—HCG水平与妊娠结局相关。正常妊娠组血清β—HCG值高于不良妊娠组（P〈0．01）；多胎妊娠组血清β—HCG值高于单胎妊娠组（P〈0．01）。以血清β-HCG〈120mIU／ml作为不良妊娠预测标准，阳性预测值为90．0％，阴性预测值为87．9％；以β-HCG〉600mIU／ml作为多胎妊娠预测标准，阳性预测值为84．6％，阴性预测值为91．1％。[结论]IVF—ET后12～14d血清β-HCG是早期预测妊娠结局的有效指标，可供正确指导咨询、及时处理参考。
[Objective] To evaluate the predictive value of serum β-HCG in pregnancy outcome 12-14 days after in vitro fertilization-embryo transfer（IVF-ET）. [Metbods] The pregnancy outcome and serum β-HCG at 12-14 days after IVF-ET in 220 cycles were retrospectively analyzed. [Results] The levels of serum β-HCG were correlated with the pregnancy outcome. The serum β-HCG levels of normal pregnancies were higher than those of poor pregnancies （P 〈 0. 01） and levels of multiple pregnancies were higher than those of singleton pregnancies（P 〈 0. 01）. Based on the cutoff value of β-HCG 〈 120 mIU/ml in predicting poor pregnancy, the positive predictive value （PPV） was 90.0% ,the negative predictive value （NPV） was 87.9%. Based on the cutoff value of β-HCG 〉 600 mIU/ml in predicting multiple pregnancy, the PPV was 84.6% ,the NPV was 91.1%. [Conclusion] The serum β-HCG at 12-14 days after IVF-ET is an effective predictor for pregnancy outcome,which may provide a reference for clinical counseling and management.
出处
《海峡预防医学杂志》
CAS
2007年第1期14-15,共2页
Strait Journal of Preventive Medicine
