摘要
目的了解肾脏疾病患者医院感染的临床特点、病原菌的分布及耐药情况,为预防和治疗肾脏疾病患者的感染提供依据。方法回顾性调查2004年1月-2006年2月肾脏疾病住院患者分离出的病原菌。结果从223例患者的各种临床标本分离出240株病原菌,其中革兰阴性杆菌占55.4%,革兰阳性球菌占26.3%,真菌占10.0%,革兰阳性杆菌占8.3%;阳性率最高的为大肠埃希菌,其次为副流感嗜血菌;分离的菌株有54.2%来自于尿液标本,其次为痰标本21.3%;分离菌株对临床常用抗菌药物表现不同程度的耐药性;混合感染率不高。结论肾脏疾病患者医院感染的病原菌以肠杆菌科细菌为主,主要为多重耐药的大肠埃希菌,引起的泌尿系统感染。
OBJECTIVE To investigate the profile of pathogen of infection in kidney disease patients. METHODS Pathogen of infection in kidney disease patients in our hospital from Jan 2004 to Feb 2006 was retrospectively investigated. RESULTS A total of 240 pathogen strains were isolated from 223 cases. Of the 240 isolated strains the rate of strains of Gram-negative bacilli was 55.4%, that of the Gram-positive cocci was 26.3%, the rate of fungi was 10. 0%and that of the Gram-positive bacilli was 8. 3%. The positive rate of Escherichia coli was the highest followed by Haemophilus influenzae. 54. 2% Of isolates were from urine, 21.3% from sputum. The isolated pathogens resisted at different degrees to antibiotics which were used frequently in clinic. The rate of polyinfection was not high. CONCLUSIONS Pathogen of infection in kidney disease patients is mainly Enterobacteriaceae. The isolates mainly are E. coli which is multi-resistant. It mainly causes the urinary infections.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2007年第2期157-159,共3页
Chinese Journal of Nosocomiology
