6McLaren AC,McLaren SG,Nelson CL,et al.The effect of sampiing method on the elution of tobramycin from calcium sulfate[J].Clin Orthop,2002,403:54-57.
7Turner TM,Urban RM,Hall DJ,et al.Local and systemic levels of tobramycin delivered from calcium sulfate bone graft substitute pellets[J].Clin Orthop,2005,437:97-104.
8Burd TA,Anglen JO,Lowry KJ,et al.In vitro elution of tobramycin from bioabsorbable polycaprolactone beads[J].J Orthop Trauma,2001,15:424-428.
9Ambrose CG,Clyburn TA,Louden K,et al.Effective treatment of osteomyelitis with biodegradable microspheres in a rabbit model[J].Clin Orthop,2004,421:293-299.
10Kim HW,Knowles JC,Kim HE,et al.Development of hydroxya patite bone scaffold for controlled drug release via poly (epsiloncaprolactone) and hydroxyapatite hybrid coatings[J].J Biomed Mater Res,2004,70B:240-249.
2Templeman DC, Gumlli B, Tsukayama DT, et al. Update on the management of open fractures of the tibial shaft. Clin Orthop, 1998, 350:18-25.
3Watson JT, Anders M, Moed BR. Management strategies for bone loss in tibial shaft fractures. Clin Orthop, 1995, 315:138-152.
4Muhr G, Ostermann P. Treatment of open fractures exemplified by tibial shaft fracture. Z Arztl Fortbild Qualitatssich, 1997, 91:415-419.
5Moehring HD, Gravel C, Chapman MW, et al. Comparison of antibiotic beads and intravenous antibiotics in open fractures. Clin Orthop, 2000, 372:254-610.
6Keating JF, Blachut PA, O′ Brien PJ, et al. Reamed nailing of open tibial fractures: does the antibiotic bead pouch reduce the deep infection rate? J Orthop Trauma, 1996, 10:298-303.
7Ostermann PA, Seligson D, Henry SL. Local antibiotic therapy for severe open fractures. A review of 1085 consecutive cases. J Bone Joint Surg(Br), 1995, 77:93-97.
8Hansis M. When is antibiotic prophylaxis required? Langenbecks Arch Chir Suppl Kongressbd, 1996, 113:708-712.
9Jacob E, Setterstrom JA, Bach DE, et al. Evaluation of biodegradable ampicillin anhydrate microcapsules for local treatment of experimental staphylococcal osteomyelitis. Clin Orthop,1991,267:237-244.
10Patzakis MJ, Bains RS, Lee J, et al. Prospective, randomized, double-blind study comparing single-agent antibiotictherapy, ciprofloxacin, to combination antibiotic therapy in open fracture wounds. J Orthop Trauma, 2000, 14:529-533.