摘要
目的了解静滴和口服红霉素对糖尿病胃轻瘫的作用。方法对１４例糖尿病胃轻瘫的患者采用静滴和口服红霉素治疗４周后，用放射性核素９９ｍＴＣ标记７１７树脂制备固体实验餐做胃排空检查。结果２小时胃残留率分别为２０％和４１％，明显低于治疗前的８８％，总的症状积分由治疗前的３９下降到３０。１４例完成４周口服红霉素治疗的患者，无严重毒副作用发生。结论红霉素是一新的、强的促胃动力药，长期应用是有效的和相对安全的。
Objective: To investigate the influence of intravenous and oral erythromycin on diabetic gastroparesis. Methods: After 16 cases of gastroparesic patients were treated for 4 weeks by intravenous erythromycin, and oral erythromycin respectively, Solid meal was made with 717 resin labelled with 99m TC and the gastric emptying of solid meal was observed, Results: Retention of meal at 120 min decreased from 88% at baseline to 20% following intravenous erythromycin and to 41% after 4 weeks of oral therapy. There was a reduction in total symptom scores from 39 to 30 and there was no severe side-effects after 4 weeks of oral erythromycin. Conclusion: Erythromycin has a strong gastric prokinetic effect and may represent a useful and safe therapeutic approach to diabetic gastroparesis
出处
《泰山医学院学报》
1996年第4期305-307,共3页
Journal of Taishan Medical College
