摘要
目的获取新生儿头罩给氧时供氧浓度(FsO2)、流量(Flow)与吸入氧浓度(FiO2)变化关系数据,探讨新生儿合理用氧的规律。方法用空气-氧气混合器调节FsO2和Flow,测定不同FsO2和Flow下,新生儿鼻前庭的O2浓度。结果(1)当FsO2为100%,Flow>3(L/min)时,各组头罩内新生儿鼻前庭氧浓度均>40%;Flow≥7(L/min)时,头罩内新生儿鼻前庭氧浓度在大、中头罩各组均接近60%,小头罩各组均>60%。(2)在同一型号头罩内,FsO2≥21%时,各组的头罩内新生儿的鼻前庭氧浓度差异均有统计学意义(P<0·01)。(3)在3种型号头罩内,FsO2的变化和Flow的变化均与新生儿的鼻前庭氧浓度的变化呈直线正相关关系(P均为0·000)。结论在头罩给氧下,FiO2随FsO2和Flow变化范围较大;用纯氧时,保持FiO2在安全值之下所要求的Flow较低;因此,应用空气-氧气混合器来选择合适的FsO2和Flow对于临床安全使用头罩供氧十分必要。
Objective To study the relationships between supplied oxygen concentration （FsO2）, flow rate （flow） and inhaled oxygen concentration （FiO2 ） in neonates when oxygen is given via oxygen hood; and to study what are the most effective ways of supplying oxygen in neonates. Methods Oxygen concentrations were measured in nasal cavities of neonates when different FsO2 and Flow were given. FsO2 and Flow were adjusted and measured by Air-oxygen blender and Pigeon I analyzer. Results When FsO2 was 100% and Flow was greater than 3 L/min, the oxygen concentration measured in nasal cavities of neonate was greater than 40% in all groups with different sizes of oxygen hood ; when Flow was increased to or greater than 7L/min, the oxygen concentrations in nasal cavities of neonate were close to 60% for groups with medium and big oxygen hood and greater than 60% for groups with small oxygen hood. Among the groups with same size oxygen hood, the difference of oxygen concentration in nasal cavities showed statistical significance （P 〈 0. 01 ） when FsO2 was equal to or greater than 21%. The oxygen concentrations in nasal cavities and the changes of FsO2 and Flow showed linear relationships （ P = 0. 000） in all studied groups with three different sizes of oxygen hood. Conclusions When oxygen is given via oxygen hood, FiO2 changes in a wide range with the changes of FsO2 and Flow; when 100 % oxygen is given, low flow is required to keep FiO2 in a satisfied range. Therefore, for the safety of oxygen supply, it is important to use air-oxygen blender to choose the right FsO2 and flow when oxygen is given via oxygen hood.
出处
《中国新生儿科杂志》
CAS
2007年第1期6-9,共4页
Chinese Journal of Neonatology
关键词
氧耗量
鼻
治疗结果
新生儿
Oxygen consumption
Nose
Treatment outcome
