摘要
我们报道了肾囊内胰岛移植治疗Ⅰ型糖尿病患者6例。其中2例停用胰岛素治疗,2例中1例停用胰岛素至今已36个月。另4例每日胰岛素用量也大为减少。全部6例患者空腹血浆 C-肽水平由移植前的0.184±0.06pmol/ml 升至移植后的0.376±0.06pmol/ml(P<0.01)。餐后2小时血浆 C-肽水平由移植前的0.334±0.09pmol/ml 升至移植后的1.094±0.13pmol/ml(P<0.01)。本研究提示,肾囊内胰岛移植治疗Ⅰ型糖尿病临床疗效显著,移植物可能长期存活。
Six cases of type Ⅰ diabetes mellitus were treated with pancreas islet transplantation into the capsule of kidney.In 2 cases insulin was discontinued and the withdrawal time of patient being 36 months.The daily dosages of insulin were decreased remarkably in the other 4 cases.In all the 6 cases fasting serum C-peptide levels rose from 0.184±0.06 pmol/ml to 0.376±0.06 pmol/ml (P<0.01),and the serum C-peptide levels of post-diet 2h from 0.334±0.09 pmol/ml to 1.094±0.13pmol/ml (P<0.01).The result showed that the islet transplantation into the cap- sule of kidney is an effective therapy for type Ⅰ diabetes mellitus.The graft may have a long-term survival.
出处
《中华器官移植杂志》
CAS
CSCD
1996年第4期183-185,共3页
Chinese Journal of Organ Transplantation
关键词
Ⅰ型糖尿病
肾囊内
胰岛移植
Type I diabetes mellitus
Pancreas islet transplantation into capsule of kidney
