摘要
室管膜下区(SVZ)是指沿着整个脑室侧壁分布的区域,在成年哺乳动物终生存在着神经发生。许多神经退行性疾病的病理过程可促进该区域的神经发生,这些新生的SVZ区神经细胞可以迁移到病灶处,以取代或修复死亡或损伤的细胞。本文介绍了成体SVZ的起源、结构特征和近几年来SVZ神经发生与神经退行性疾病相关性研究的进展。
The neurogenesis in subventricular zone（SVZ）, which is located in the lateral wall of the lateral ventricle, is observed throughout the lifetime in mammalian. The studies suggested neurogenesis could be stimulated further by pathological processes and newly generated neurons might be capable of replacing loss cells in neurological diseases. This paper overviewed the source, composition and architecture of the adult SVZ neurogenesis and the progress of the correlationship between SVZ neurogenesis and neurodegenerative diseases in the recent years.
出处
《中国临床神经科学》
2007年第1期92-95,共4页
Chinese Journal of Clinical Neurosciences
