摘要
大鼠腹腔注射野百合碱50mg/kg.3周后形成肺动脉高压并伴有右室肥大。粉防已碱每次10mg/kg及15mg/kg,每日2次灌胃能抑制野百合碱形成肺动脉高压及右室肥大的作用。
Pulmonary hypertension and right ventricular hypertrophy in rats were developed 3 weeks after administration of monocrotaline 50mg/kg ip. Tetrandrine 10mg/kg and 15mg/kg bid po could prevent the above-said effects produced by monocrotaline.
出处
《中国中药杂志》
CAS
CSCD
北大核心
1996年第12期751-752,共2页
China Journal of Chinese Materia Medica
关键词
野百合碱
肺动脉高压
粉防己碱
monocrotaline
pulmonary hypertension
tetrandrine
