摘要
以亚甲基兰为模型药物,选取0.1mol/L的盐酸、pH7.4的磷酸缓冲液(PBS)、生理盐水(PS)为介质,分别模拟人体的胃、肠、体液环境,考察淀粉微球的载药性能。以淀粉微球为修饰剂制作修饰碳糊电极,作为工作电极,以电活性的抗坏血酸为模型药物,采用伏安扫描法研究淀粉微球对药物的吸附机理。
The drug carrying properties of starch micro-sphere were evaluated in three different media： 0.1mol/L hydrochloric acid, pH7.4 phosphate buffer succi（PBS）, physiological saline（PS） with methylene blue as model drug. The adsorptive mechanism of starch micro-sphere was studied by means of eletrachemical method using ascorbic acid（AA） as model drug, using starch micro-sphere as agent prepare chemical modefied carbonic parafin electrode（CMCPE）.
出处
《食品科技》
CAS
北大核心
2007年第1期35-38,共4页
Food Science and Technology
基金
国家自然基金项目(50573046)。
关键词
淀粉微球
吸附机理
修饰电极
模拟药物
starch micro-sphere
adsorptive mechanism
modified electrode
model drug
