摘要
细胞外信号调节激酶信号通道是一条重要的细胞内传导通道。它参与了细胞的生长、发育、增殖、分化及恶性转化等多个生理和病理生理过程，近年来有关该通道在支气管哮喘发病机制中的作用成为研究的热点。本文就该通道的生物学特征、研究方法及其在哮喘发病机制中的作用进行简要综述。
Extracellular signal-regulated kinase （ERK） signaling pathway is a critical signaling pathway that transduce the intracellular signal. It participate in several physiological and pathphysiological processes of celluar growth, development, proliferation, differentiation and malignant transformation. In recent years, many studies focus on pathogenesis of bronchial asthma. It is reviewed of ERK signaling pathway about the biological characteristic, methods of investigation and action in the pathogenesis of asthma.
出处
《国际呼吸杂志》
2007年第1期19-22,共4页
International Journal of Respiration
基金
国家自然科学基金资助项目（30400195）和武汉市科技计划项目（20045006071-8）
关键词
细胞外信号调节激酶
信号通道
哮喘
Extracellular regulated signal kinase
Signaling pathway
Asthma
