摘要
目的:通过分析上海市药品不良反应中心收到的药品不良反应(ADR)报告中,头孢菌素类抗生素所致的ADR及其相关因素,了解该类药物ADR发生的情况,以减少ADR的发生。方法:采用回顾性调查方法对2003年6月-2005年2月上海市药品不良反应中心收到的头孢菌素类抗生素所致1 333例ADR报告进行统计分折。结果:ADR涉及药品排前3位的是头孢噻肟、头孢拉定和头孢曲松。ADR累及系统以皮肤及其附件损害为最多。结论:应用头孢菌素类抗生素时应关注其ADR,提高安全用药水平。
Objective： To investigate the characteristics of adverse drug reaction （ADR） induced by cephalosporins through the analysis of ADR reports from ADR Monitoring Centre of Shanghai. Methods. A retrospective investigation into 1 333 eases of ADR of eephalosporins collected by ADR Monitoring Centre of Shanghai from June 2003 to February 2005 was carried out. Results： Top 3 drugs related to ADR were cefotaxime, cefradine and ceftriaxone. Skin and its accessories damage accounted for the highest percentage of ADR of cephalosporins. Conelusion t It is important to pay attention to the ADR of eephalosporins and to improve the use of these drugs.
出处
《药学服务与研究》
CAS
CSCD
2006年第6期440-442,共3页
Pharmaceutical Care and Research
关键词
头孢菌素类
药物副反应报告系统
药疹
cephalosporins
adverse drug reaction reporting systems
drug eruptions
