阴茎勃起的信号通路研究进展
摘要
对国内外近年来参与阴茎勃起过程中的四条信号通路及分子机制的研究进行回顾,从平滑肌收缩和舒张两方面进行总结,以期能更好地理解ED的发生机制。
出处
《国际泌尿系统杂志》
2007年第1期50-55,共6页
International Journal of Urology and Nephrology
参考文献42
-
1Stefan Uckert,Petter Hedlund,Eginhard Waldkirch,Michael Sohn,Udo Jonas,Karl-Erik AnderssonChristian G.Stief.Interactions between cGMP-and AMP-pathways are involvedin the regulation of penile smooth muscle tone.World J Urol,2004,22:261 -266.
-
2Andersson KE.Pharmacology of lower urinary tract smooth muscles and penile erectile tissues.Pharmacol Rev,1993,45:253-309.
-
3Stephen L.Archer.Potassium channels and erectile dysfunction.Vascular Pharmacology,2002,38:61-71.
-
4Park KH,Kim SW,Kim KD,et al.Effects of androgens on the expression of nitric oxide synthase mRNAs in rat corpus cavernosum.Br J Urol,1999,83:327-333.
-
5Naomi Hosogai,Shoji Takakura,Toshitaka Manda.Enzyme ctivities of the nitric oxide-cGMP pathway in corpus cavernosum isolated from middle-aged rats.European Journal of Pharmacology,2003,473:65-70.
-
6Shaohua Chang,Joseph A.Hypolite,Marielena Velez.Downregulation of cGMP-dependent protein kinase-1 activity in the corpuscavernosum smooth muscle of diabetic rabbits.Am J Physiol Regul Integr Comp Physiol,2004,287:950-960.
-
7Trinity J,Bivalacqua,Mustafa F.Gene transfer of endothelial nitric oxide synthase partially restores nitric oxide synthesis and erectile function in streptozotocin diabetic rats.J Urol,2003,169:1911 -1917.
-
8Petter Hedlund,Attila Aszo di,Alexander Pfeifer.Erectile dysfunction in cyclic GMP-dependent kinase I-deficient mice.PNAS,2000,97 (5):2349 -2354.
-
9Javier Angulo,Pedro Cuevas,Argentina Fern_andez.Diabetes impairs endothelium-dependent relaxation of human penile vascular tissues mediated by NO and EDHF.Biochemical and Biophysical Research Communications,2003,312:1202-1208.
-
10Allen D,Seftel,Nosratola D,et al.Advanced glycosylation end products In human penis:elevation in diabetic tissue,site of deposition,and possible effect through iNOS or eNOS,UROLOGY,1997,50(6):1016-1026.
二级参考文献8
-
1Yu-TianDAI,VivienneStopper,RonaldLewis,ThomasMills.Effects of castration and testosterone replacement on veno-occlusion during penile erection in the rat[J].Asian Journal of Andrology,1999,1(1):53-59. 被引量:4
-
2Burnett AL,Lowenstein CJ,Bredt DS,et al.Nitric oxide:a physiologic mediator of penile erection[].Science.1992
-
3Garban H,Marquez D,Magee T,et al.Cloning of rat and humaninducible penile nitric oxide synthase.Application for gene therapyof erectile dysfunction[].Biology of Reproduction.1997
-
4Feldman HA,Goldstein I,Hatzichristou DG,et al.Impotence and its medical and psychosocial correlates:results of the Massachusetts Male Aging Study[].Journal d Urologie.1994
-
5Gonzalez-Cadavid NF,Ignarro LJ,Rajfer J.N itric oxide and the cyclic GMP system in the penis[].MolUrol.1999
-
6Magee T,Fuentes AM,Garban H,et al.Cloning of a novel neuronal nitric oxide synthase expressed in penis and lower urinary tract[].Biochemical and Biophysical Research Communications.1996
-
7Carrier S,Nagaraju P,Morgan DM,et al.Age decreases nitric oxide synthase-containing nerve fibers in the rat penis[].Journal d Urologie.1997
-
8Ferrini M,Magee TR,Vernet D,et al.Aging-related expression of inducible nitric oxide synthase and markers of tissue damage in the rat penis[].Biology of Reproduction.2001
共引文献21
-
1戴玉田,孙则禹,Chitaley K,Webb RC,Mills TM,Lewis RW.应用Rho激酶抑制剂对大鼠阴茎勃起的作用[J].中华男科学杂志,2004,10(8):589-592. 被引量:5
-
2李建伟,王国政,秦文波,杨宇如.衰老对大鼠阴茎海绵体内皮细胞功能的影响[J].中华男科学杂志,2004,10(11):824-826.
-
3黄兴,胡礼泉,田斌群.老年大鼠勃起功能及阴茎组织中nNOS神经纤维的改变[J].医学新知,2004,14(4):237-238.
-
4黄兴,胡礼泉,田斌群.生长激素促进老年大鼠阴茎组织中nNOS神经纤维的再生[J].中华男科学杂志,2005,11(2):98-100.
-
5张贤生,王益鑫,韩银发,李铮,向祖琼,冷静,黄旭元.生长激素补充对老龄大鼠勃起功能及阴茎海绵体nNOS表达的影响[J].中华男科学杂志,2005,11(5):339-342. 被引量:5
-
6刘波,刘继红,王涛,肖恒军,陈俊,罗冬喜,叶章群.衰老对大鼠阴茎组织诱导型一氧化氮合酶的表达和细胞凋亡的影响[J].中华男科学杂志,2006,12(3):251-253. 被引量:12
-
7陈岽,戴玉田,陈赟,孙则禹.晚期糖基化终产物对大鼠阴茎海绵体组织中一氧化氮含量及其合成酶活性的影响[J].南京大学学报(自然科学版),2007,43(2):157-163. 被引量:4
-
8夏川,姜睿.RhoA/Rho激酶在阴茎勃起中的作用[J].中华男科学杂志,2007,13(6):546-549. 被引量:4
-
9刘云飞,陈实新,邢金春,陈斌,刘荣福,周中泉.自发性高血压大鼠阴茎海绵体组织内皮型一氧化氮合酶的表达及意义[J].中国男科学杂志,2007,21(9):4-7. 被引量:2
-
10黄明玉.老年性性功能减退的研究现状与前景[J].现代中西医结合杂志,2008,17(4):637-638.
-
1王靖平,李盼荣.蜂螫伤致休克一例[J].北京军区医药,2000,12(1):73-73.
-
2陈英德.硫酸镁治疗胆石症的体会[J].现代中西医结合杂志,2007,16(28):4104-4104. 被引量:3
-
3得了前列腺炎时还能有“性”吗[J].人人健康,2008,0(13):57-57.
-
4陈育民.胆绞痛为何常在夜间发作?[J].祝您健康,2012(11):27-27.
-
5楼水鑫.多沙唑嗪在良性前列腺增生引起的急性尿潴留(AI)中的作用[J].现代泌尿外科杂志,2007,12(4):273-273.
-
6谢立平,白宇.良性前列腺增生症下尿路症状的治疗进展[J].中华老年医学杂志,2006,25(11):873-875. 被引量:4
-
7朱燕中.前列腺是人体重要的生殖器官[J].祝您健康,1995,0(5):8-8.
-
8王爱云,葛英,王丽娜,曹利荣,罗宏.音乐震荡式助尿器的临床应用[J].中华护理杂志,2001,36(10):727-727. 被引量:2
-
9宫大鑫.多沙唑嗪可有效治疗良性前列腺增生症[J].中华男科学杂志,2007,13(5):474-474. 被引量:1
-
10崔永.西地那非体外抑制几内亚猪膀胱的收缩[J].中国男科学杂志,2007,21(6):66-66.