5Fahy J,Irvin C,Peter SP,et al.Proceedings of ATS workshop on refractory asthma-current understanding,recommendations and unanswered questions[J].Am J Respir Crit Case Med,2000,162(6):2241-2351.
7Holgate S,Bousquet J,Wenzel S,et al.Efficacy of omalizumab,an anti-immunoglobulin E antibody,in patients with allergic asthma at high risk of serious asthma-related morbidity and mortality[J].Curr Med Res Opin,2001,17(4):223-240.
二级参考文献39
1Gern JE,Busse WW.The role of viral infection in the natural history of asthma.J Allergy Clin Immunol,2000,106(2):201-212.
2Kraft M,Cassell GH,Henson JE,et al.Detection of Mycoplasma pneumoniae in the Airways of Adults with Chronic Asthma.Am J Respir Crit Care Med,1998,158(9):998-1001.
3Leung DY,Cassed GH,Gutierrez J,et al.T cell response to Mycoplasma pneumoniae in patients with chronic asthma,J Allergy Clin Immunol,2002,109 (1):S26.
4Hahn DL.Chlamydia pneumoniae,asthma,and COPD:what is the evidence? Ann Allergy Asthma Immunol,1999,83 (4):271-288.
5Yamada K,Elliott WM,Brattsand R,et al.Molecular mechanisms of decreased steroid responsiveness induced by latent adenoviral infection in allergic lung inflammation.J Allergy Clin Immunol,2002,109 (1):35-42.
6Hauk PJ,Hamid QA,Chrousos GP,et al.Induction of corticosteroid insensitivity in human PBMCs by microbial superantigens.J Allergy Clin Immunol,2000,105 (4):782-787.
7Hearing SD,Norman M,Smyth C,et al.Wide variation in lymphocyte steroid sensitivity among healthy human volunteers.J Clin Endocrinol Metab,1999,84(11):4149-4154.
8Xu Q,Leung DY,Kisich KO.Serine-arginine-rich protein p30 directs alternative splicing of glucocorticoid receptor pre-mRNA to glucocorticoid receptor-β in neutrophils.J Biol Chem,2003,278(7):27112-27118.
9Sousa AR,Lane SJ,Soh C,et al.In vivo resistance to corticosteroids in bronchial asthma is associated with enhanced phosphorylation of jun N-terminal kinase phosphorylation.J Allergy Clin Immunol,1999,104 (9):565-574.
10Richards DF,Fernandez M,Caulfield J,et al.Glucocorticoids drive human CD8+ T cell differentiation towards a phenotype with high IL-10 and reduced IL-4,1L-5 and 1L-13 production.Eur J Immunol,2000,30(8):2344-2354.
