摘要
经检测，对钴－６０辐照，病人血清中ＨＢｓＡｇ、ｐＨＳＡ－Ｒ与ＨＢＶ－ＤＮＡ抗力较其中ＨＢＶ－ＤＮＡｐ、ＨＢｅＡｇ及纯化ＨＢｓＡｇ者为强．ＨＢＶ颗粒经１７．９０ｋＧｙ剂量辐照后在电镜下仅见碎片．对所试含氯消毒剂、碘酊、高锰酸钾、盐酸与过氧化物消毒剂，病人血清中的ＨＢｓＡｇ较其中ｐＨＳＡ－Ｒ、ＨＢｅＡｇ及纯化ＨＢｓＡｇ的抗力为强．
The resistance of serological markers of hepatitis B to 60Co irradiation and some chemi-cal disinfectants was examined in laboratory.The results were as follows: 1 : 10 diluted se- rum HBsAg and pHSA- Rand undiluted serum H BV- DNA from patient had strong resist ance to60Co irradiation with a destructive dosage of 2 1.50 kGy; the serum H BV- DN Ap,HBcAg and purified HBsAg had weaker resistance to60Co irradiation, after exposure to 17.9kGy irradiation, only fragments of HBV particles could be seen under electronmicroscope.In regard to the chemical disinfectants tested,pH SA- Rand H BeAg in 1: 10 diluted pa-tient、serum and purified HBsAg were destroyed by 3.0% chloramine T,2.0% tincture iodi,2.0%hydrochloric acid and 0.1%potassium permanganate after exposure for 5 minutes.tvhile HBsAg in serum of patient was not. Both HBsAg, pHSA-R, HBeAg in patient's serumand purified H BsAgcould be destroyed by 0.5%peracetic acid, but could not be destroyed by3.0% hydrogen peroxide.The experimental results also indicated that the concentration of markers and serum con-tent had influence on efficacy of60Co irradiation in destroying HBsAg.
出处
《中国消毒学杂志》
CAS
北大核心
1996年第4期197-201,共5页
Chinese Journal of Disinfection
关键词
乙型肝炎病毒
灭活
标志物
钴-60照射
消毒剂
inactivation of HBV marker of hepatitis B 60Co irradiationodium dichloroisocyanurate peracetic acid hydrogen peroxide tinctura iodipotassium permanganate
