摘要
在大白兔动脉粥样硬化模型上，观察复方仙灵颗粒剂抗动脉粥样硬化的作用。结果表明：复方仙灵颗粒剂组其主动脉粥样硬化斑块覆盖面积明显少于高脂饲料组；抗动脉粥样硬化的作用优于中药舒冠片。其机制与抗氧自由基、降低血清胆固醇和调节ＴＸＡ＿２／ＰＧＩ＿２平衡有关。
his study was to eveluate the anti-atherosclerotic effect of Epimedium compound granules(ECG).Forty Japanese white rabbits were divided into four groups:l.normally fed groups(N);2.high-lipid-fed groups(HL);3.treatment of groups of ECG(EC);4.treatment of control groupsof Shuguan pian(SG).The results indicated that the area of atherosclerotic plaque coverage inaortaof ECG groups were much smaller than those of HL groups.The protective mechanism is concerned with anti-oxygen free radicals,decreasing of serum cholesterol and regulation of bal-ance of TXA_2/PGI_2.The EC is a new drug,whose anti-atherosclerotic effect is stronger thanthat of chinese medicine-SG.
出处
《湖南医科大学学报》
CSCD
1996年第6期469-472,共4页
Bulletin of Hunan Medical University
基金
湖南省科委资助项目
关键词
动脉粥样硬化
复方仙灵颗粒剂
中医药疗法
atherosclerosis
Epimedium compound granules
oxygen free radicals
superoxide dismutase
TXA_2
PGI_2
rabbits(Department of Pathophysiology,Hunan Medical University)
