摘要
抗瘤Ⅰ号（ＡＴ－Ⅰ）是临床抗肿瘤及肿瘤辅助治疗的有效复方中药制剂。实验检测了ＡＴ－Ⅰ对正常及荷瘤小鼠体内ＩＬ－２、ＩＬ－６产生及ＮＫ细胞活性的影响，结果显示ＡＴ－Ⅰ对正常小鼠ＩＬ－２、ＩＬ－６及荷瘤小鼠ＩＬ－２产生均有促进作用；同时还能提高正常及荷瘤小鼠ＮＫ细胞的杀伤活性，提示ＡＴ－Ⅰ是具有生物反应调节作用的中药制剂。
Antitumor Ⅰ(AT Ⅰ) is a traditional Chinese medicine,which known to be combined with chemotherapeutic agent on antitumor effects.In this paper,the effections of AT Ⅰ on interleukin 2(IL 2) and interleukin 6(IL 6) was detected and NK cell activity were observed in normal and tumorbearing BALB/c mice in vivo.The results showed that AT Ⅰcould enhance IL 2 and IL 6 production in normal mice,and IL 2 product in tumor bearing mice. The results suggest that AT Ⅰ at a appropriate dose could modulate immunofunctions,so known as a biological respose modifier(BRM).
出处
《华西医科大学学报》
CSCD
1996年第4期378-382,共5页
Journal of West China University of Medical Sciences
关键词
抗瘤Ⅰ号
白细胞介素2
抗癌药
NK细胞
Antitumor Ⅰ(AT Ⅰ) Interleukin 2 Interleukin 6 Natural killer cells
